Nuclear export of messenger RNA

J Katahira - Genes, 2015 - mdpi.com
Transport of messenger RNA (mRNA) from the nucleus to the cytoplasm is an essential step
of eukaryotic gene expression. In the cell nucleus, a precursor mRNA undergoes a series of …

Roles of the TREX complex in nuclear export of mRNA

J Katahira, Y Yoneda - RNA biology, 2009 - Taylor & Francis
Recent studies have established that nuclear export of mRNAs is functionally coupled to
different steps in gene expression processes, such as transcription, splicing, 3'-end …

[PDF][PDF] Two closely related human nuclear export factors utilize entirely distinct export pathways

J Yang, HP Bogerd, PJ Wang, DC Page, BR Cullen - Molecular cell, 2001 - cell.com
Nuclear mRNA export mediated by the human protein TAP requires a carboxy-terminal
domain that directly interacts with components of the nuclear pore complex. Here we …

The C-terminal domain of TAP interacts with the nuclear pore complex and promotes export of specific CTE-bearing RNA substrates

A BACHI, IC BRAUN, JP RODRIGUES, N PANTÉ… - Rna, 2000 - cambridge.org
Messenger RNAs are exported from the nucleus as large ribonucleoprotein complexes
(mRNPs). To date, proteins implicated in this process include TAP/Mex67p and RAE1/Gle2p …

RNA export mediated by tap involves NXT1-dependent interactions with the nuclear pore complex

L Lévesque, B Guzik, T Guan, J Coyle, BE Black… - Journal of Biological …, 2001 - ASBMB
Nuclear export of ribonucleoprotein complexes requires cis-acting signals and recognition
by receptors that mediate translocation through the nuclear pore complex. Translocation is …

The human Tap protein is a nuclear mRNA export factor that contains novel RNA-binding and nucleocytoplasmic transport sequences

Y Kang, BR Cullen - Genes & development, 1999 - genesdev.cshlp.org
The constitutive transport element (CTE) encoded by simian type D retroviruses directs
unspliced viral RNAs into a nuclear export pathway that is congruent with the pathway used …

Polyadenylation and nuclear export of mRNAs

M Stewart - Journal of Biological Chemistry, 2019 - ASBMB
In eukaryotes, the separation of translation from transcription by the nuclear envelope
enables mRNA modifications such as capping, splicing, and polyadenylation. These …

Nuclear mRNA export: insights from virology

BR Cullen - Trends in biochemical sciences, 2003 - cell.com
To maximize the production of progeny virions, several viruses have evolved mechanisms
that promote the selective nuclear export of viral mRNA transcripts while, in some cases …

The human tap nuclear RNA export factor contains a novel transportin-dependent nuclear localization signal that lacks nuclear export signal function

R Truant, Y Kang, BR Cullen - Journal of Biological Chemistry, 1999 - ASBMB
The human Tap protein mediates the sequence-specific nuclear export of RNAs containing
the constitutive transport element and is likely also critical for general mRNA export. Here …

Formation of Tap/NXT1 heterodimers activates Tap-dependent nuclear mRNA export by enhancing recruitment to nuclear pore complexes

HL Wiegand, GA Coburn, Y Zeng, Y Kang… - … and cellular biology, 2002 - Am Soc Microbiol
The Tap protein has been shown to activate the nuclear export of mRNA species bearing
retroviral constitutive transport elements and is also believed to play an essential role in the …