Neurotrophic factors-based therapeutic strategies in the spinal cord injury: an overview of recent preclinical studies in rodent models
N Deznabi, S Hosseini, M Rajabi - The Egyptian Journal of Neurology …, 2023 - Springer
Following the traumatic spinal cord injury (SCI) and initial mechanical insult, a cascade of
secondary cellular and molecular events occurs at the trauma site. This phenomenon …
secondary cellular and molecular events occurs at the trauma site. This phenomenon …
Neurotrophic factors for spinal cord repair: Which, where, how and when to apply, and for what period of time?
AR Harvey, SJ Lovett, BT Majda, JH Yoon… - Brain research, 2015 - Elsevier
A variety of neurotrophic factors have been used in attempts to improve morphological and
behavioural outcomes after experimental spinal cord injury (SCI). Here we review many of …
behavioural outcomes after experimental spinal cord injury (SCI). Here we review many of …
Rodent spinal cord injury model and application of neurotrophic factors for neuroprotection
HS Sharma, A Sharma - Neurotrophic Factors: Methods and Protocols, 2012 - Springer
Spinal cord injury (SCI) is a serious clinical problem that causes lifetime disabilities to
victims and inflicting huge social burden on our society. One of the main lacunae in …
victims and inflicting huge social burden on our society. One of the main lacunae in …
Sustained delivery of neurotrophic factors to treat spinal cord injury
A Muheremu, L Shu, J Liang, A Aili… - Translational …, 2021 - degruyter.com
Acute spinal cord injury (SCI) is a devastating condition that results in tremendous physical
and psychological harm and a series of socioeconomic problems. Although neurons in the …
and psychological harm and a series of socioeconomic problems. Although neurons in the …
Fibroblast growth factors in the management of spinal cord injury
Spinal cord injury (SCI) possesses a significant health and economic burden worldwide.
Traumatic SCI is a devastating condition that evolves through two successive stages …
Traumatic SCI is a devastating condition that evolves through two successive stages …
History of glial cell line-derived neurotrophic factor (GDNF) and its use for spinal cord injury repair
MJ Walker, XM Xu - Brain sciences, 2018 - mdpi.com
Following an initial mechanical insult, traumatic spinal cord injury (SCI) induces a secondary
wave of injury, resulting in a toxic lesion environment inhibitory to axonal regeneration. This …
wave of injury, resulting in a toxic lesion environment inhibitory to axonal regeneration. This …
Role of GDNF in Spinal Cord Injury Repair
MJ Walker, XM Xu - 2018 - preprints.org
Following an initial mechanical insult, traumatic spinal cord injury (SCI) induces a secondary
wave of injury, resulting in a toxic lesion environment inhibitory to axonal regeneration. This …
wave of injury, resulting in a toxic lesion environment inhibitory to axonal regeneration. This …
Potential role of growth factors in the management of spinal cord injury
BI Awad, MA Carmody, MP Steinmetz - World neurosurgery, 2015 - Elsevier
Objective To review central nervous system growth factors and their therapeutic potential
and clinical translation into spinal cord injury (SCI), as well as the challenges that have been …
and clinical translation into spinal cord injury (SCI), as well as the challenges that have been …
Therapeutic effects of neurotrophic factors in experimental spinal cord injury models
M Enomoto - Journal of Neurorestoratology, 2016 - dovepress.com
Neurotrophic factors (NFs) play important roles in regenerative medicine approaches to
mitigate primary and secondary damage after spinal cord injury (SCI) because their …
mitigate primary and secondary damage after spinal cord injury (SCI) because their …
Present situation and future aspects of spinal cord regeneration
M Enomoto, Y Wakabayashi, ML Qi… - Journal of Orthopaedic …, 2004 - Elsevier
The central nervous system (CNS) has a limited capacity for regeneration after injury. In
spinal cord injury (SCI) patients, total loss of all motor and sensory function occurs below the …
spinal cord injury (SCI) patients, total loss of all motor and sensory function occurs below the …
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