Lipid nanoparticles (LNPs) for the efficient delivery of drugs need to be designed for the
particular administration route and type of drug. Here we report the design of LNPs for the …

Inhaled delivery of mRNA has the potential to treat a wide variety of diseases. However,
nebulized mRNA lipid nanoparticles (LNPs) face several unique challenges including …

Messenger RNA is a class of promising nucleic acid therapeutics to treat a variety of
diseases, including genetic diseases. The development of a stable and efficacious mRNA …

Introduction: Lipid nanoparticles (LNP) have been successfully used as a platform
technology for delivering nucleic acids to the liver. To broaden the application of LNPs in …

Although mRNA lipid nanoparticles (LNPs) are highly effective as vaccines, their efficacy for
pulmonary delivery has not yet fully been established. A major barrier to this therapeutic …

Lipid nanoparticles (LNPs) have emerged as a powerful non-viral carrier for drug delivery.
With the prevalence of respiratory diseases, particularly highlighted by the current COVID-19 …

Lipid nanoparticles (LNPs) have demonstrated efficacy and safety for mRNA vaccine
administration by intramuscular injection; however, the pulmonary delivery of mRNA …

Despite lipid nanoparticles'(LNPs) success in the effective and safe delivery of mRNA
vaccines, an inhalation-based mRNA therapy for lung diseases remains challenging. LNPs …

Abstract Introduction Lipid based nanoparticles (LNPs) are clinically successful vectors for
hepatic delivery of nucleic acids. These systems are being developed for non-hepatic …

In recent years, there has been an increase in deaths due to infectious diseases, most
notably in the context of viral respiratory pathogens. Consequently, the focus has shifted in …