Chronic obstructive pulmonary disease (COPD) is characterized by inflammation of the
respiratory tract in which macrophages are the predominant inflammatory cell and for which …

Down-regulation of cytokine production in activated human blood monocytes (BMs) and
alveolar macrophages (AMs) can be achieved in vitro by treatment with corticosteroids. The …

Patients with chronic obstructive pulmonary disease (COPD) are predisposed to
atherosclerosis and coronary artery disease, but the underlying mechanisms are unclear …

Chronic obstructive pulmonary disease (COPD) is characterised by a chronic inflammatory
process in the large and small airways, as well as in the lung parenchyma. Although the role …

Different inflammatory cell profiles are observed in the lungs of patients with asthma versus
those with chronic obstructive pulmonary disease (COPD). In asthma, several key mediators …

We determined the effect of inhaled corticosteroid, budesonide, on the release of the anti-
inflammatory cytokine, interleukin-10 (IL-10), and of pro-inflammatory cytokines …

There is increasing evidence that chronic obstructive pulmonary disease (COPD) is
associated with chronic inflammation in the airways and lung parenchyma; however, little is …

The role of glucocorticoids in the treatment of chronic obstructive pulmonary disease
(COPD) is controversial. We have previously described high numbers of neutrophils and …

Inhaled corticosteroids are widely prescribed for the treatment of stable chronic obstructive
pulmonary disease (COPD), despite lack of proven efficacy. Because COPD involves airway …

The present study tested the hypothesis that alveolar macrophages (AM) from patients with
chronic obstructive pulmonary disease (COPD) release more pro-inflammatory and/or less …