An association of melatonin levels with age disease initiation of autoimmune diseases and
pineal calcification was reported while an inverse association between melatonin levels and …

Melatonin is the major secretory product of the pineal gland during the night and has
multiple activities including the regulation of circadian and seasonal rhythms, and …

Psoriasis is a common, chronic, recurrent T-helper (Th1/Th17) mediated inflammatory
dermatosis, which is triggered by various factors in individuals with an appropriate genetic …

Melatonin is a hormone produced by the pineal gland. In addition to its hormonal effect, it
has strong antioxidant properties. Melatonin is probably best known for its ability to control …

Background: The neuroendocrine system is known to influence immunity, but the precise
interactions between different hormones and autoimmune disorders remain obscure. Aims …

Rheumatoid arthritis (RA) is an inflammatory joint disorder characterized by synovial
proliferation and inflammation, with eventual joint destruction if inadequately treated …

Autoimmune diseases are a broad spectrum of disorders involved in the imbalance of T-cell
subsets, in which interplay or interaction of Th1, Th17 and Tregs are most important …

Melatonin is a neurohormone mainly produced by the pineal gland following a circadian
rhythm. It is characterized as a pleiotropic factor because it not only regulates the wake …

The pineal neurohormone melatonin (MLT) has been widely shown to exert an
immunostimulatory and antiapoptotic role, mainly by acting on Th cells and on T and B cell …

Melatonin is the main hormone that regulates the sleep cycle, and it is mostly produced by
the pineal gland from the amino acid tryptophan. It has cytoprotective, immunomodulatory …