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Cancer is one of the leading causes of death in the United States, and more than 1.5 million
new cases and more than 0.5 million deaths were reported during 2010 in the United States …

Purpose: We initiated a personalized medicine program in the context of early clinical trials,
using targeted agents matched with tumor molecular aberrations. Herein, we report our …

Translational research has revolutionized how we develop new treatments for cancer
patients. The change from an organ-centric concept guiding treatment choice towards deep …

The renowned Canadian physician and McGill alumnus got it right. Much of medical science
over the past century has documented intra-and inter-individual variability, however the …

Personalized medicine (PM) is defined as “a form of medicine that uses information about a
person's genes, proteins, and environment to prevent, diagnose, and treat disease.” The …

This article provides an overview of the research, beginning a century ago, that has led to
the current use of genomically informed methods for selection of targeted therapies to treat …

In the past 10 years, the number of tools available to treat cancer has increased, as has our
understanding of what makes some cancers tick. The standard old-time cancer treatments …

Implementing personalized cancer care requires a sound understanding of cancer
genomics, familiarity with the analytical methods used to study cancer, knowledge of the …

Abstract In 2006, the Moffitt Cancer Center partnered with patients, community clinicians,
industry, academia, and 17 hospitals in the United States to begin a personalized cancer …