Objective Few studies have examined the potential interactive effect of both smoking and
drinking on cognition. Brain-derived neurotrophic factor (BDNF) plays a critical role in …

Recent studies demonstrate that brain-derived neurotrophic factor (BDNF) might be
associated with nicotine addiction, and circulating BDNF is a biomarker of memory and …

Background As a neurotoxic substance, alcohol can induce neurodegenesis in the brain.
Alcohol-dependent patients' cognitive functioning can be affected by chronic alcohol use. In …

Background Preclinical studies suggest that decreased levels of brain-derived neurotrophic
factor in the amygdala play a role in anxiety and alcohol use disorder. The association …

Chronic alcohol consumption is associated with neurocognitive and memory deficits,
dramatically affecting plasticity and connectivity, with maximal expression as dementia …

Abstract Background Brain-Derived Neurotrophic Factor (BDNF) is a neurotrophin that plays
a crucial role in neuronal survival and plasticity. Previous studies have suggested that …

Recent animal studies have suggested an association between nicotine and alterations in
brain-derived neurotrophic factor (BDNF) expression levels. However, the role of BDNF in …

Objective Although a reduction in brain-derived neurotrophic factor (BDNF) has been
implicated as a cause of cognitive impairment in type 2 diabetes mellitus (T2DM), the role of …

Heavy alcohol use reduces the levels of the brain‐derived neurotrophic factor (BDNF) in the
prefrontal cortex of rodents through the upregulation of microRNAs (miRs) targeting BDNF …

Methamphetamine (METH) is a highly addictive psychostimulant with serious neurotoxic
effects. Given evidence indicating that brain-derived neurotrophic factor (BDNF) is …