Single-cell applications of next-generation sequencing

N Anaparthy, YJ Ho… - Cold Spring …, 2019 - perspectivesinmedicine.cshlp.org
The single cell is considered the basic unit of biology, and the pursuit of understanding how
heterogeneous populations of cells can functionally coexist in tissues, organisms, microbial …

[HTML][HTML] Single cell analysis: from technology to biology and medicine

X Pan - Single cell biology, 2014 - ncbi.nlm.nih.gov
Single-cell analysis heralds a new era that allows “omics” analysis, notably genomics,
transcriptomics, epigenomics and proteomics at the single-cell level. It enables the …

Single cell sequencing: technique, application, and future development

R Xue, R Li, F Bai - Science Bulletin, 2015 - Elsevier
The progression of next generation sequencing is continuously changing the landscape of
genomic, transcriptomic, and epigenomic studies. Particularly, advances in single cell …

Single‐cell sequencing in translational cancer research and challenges to meet clinical diagnostic needs

U Pfisterer, J Bräunig, P Brattås… - Genes …, 2021 - Wiley Online Library
The ability to capture alterations in the genome or transcriptome by next‐generation
sequencing has provided critical insight into molecular changes and programs underlying …

The single-cell sequencing: new developments and medical applications

X Tang, Y Huang, J Lei, H Luo, X Zhu - Cell & bioscience, 2019 - Springer
Single-cell sequencing technologies can be used to detect the genome, transcriptome and
other multi-omics of single cells. They can show the differences and evolutionary …

Single-cell sequencing in precision medicine

JE Wiedmeier, P Noel, W Lin, DD Von Hoff… - Precision Medicine in …, 2019 - Springer
The application of next-generation sequencing in cancer genomics allowed for a better
understanding of the genetics and pathogenesis of cancer. Single-cell genomics is a …

Single-cell sequencing technologies: current and future

J Liang, W Cai, Z Sun - Journal of Genetics and Genomics, 2014 - Elsevier
Intensively developed in the last few years, single-cell sequencing technologies now
present numerous advantages over traditional sequencing methods for solving the problems …

Single cell sequencing: a distinct new field

J Wang, Y Song - Clinical and translational medicine, 2017 - Springer
Single cell sequencing (SCS) has become a new approach to study biological
heterogeneity. The advancement in technologies for single cell isolation, amplification of …

Applications of single-cell DNA sequencing

GD Evrony, AG Hinch, C Luo - Annual review of genomics and …, 2021 - annualreviews.org
Over the past decade, genomic analyses of single cells—the fundamental units of life—have
become possible. Single-cell DNA sequencing has shed light on biological questions that …

Single-cell sequencing-based technologies will revolutionize whole-organism science

E Shapiro, T Biezuner, S Linnarsson - Nature Reviews Genetics, 2013 - nature.com
The unabated progress in next-generation sequencing technologies is fostering a wave of
new genomics, epigenomics, transcriptomics and proteomics technologies. These …