Phycocyanin improves reproductive ability in obese female mice by restoring ovary and oocyte quality

X Wen, Z Han, SJ Liu, X Hao, XJ Zhang… - Frontiers in Cell and …, 2020 - frontiersin.org
Reproductive dysfunction associated with obesity is increasing among women of
childbearing age. Emerging evidence indicates that maternal obesity impairs embryo …

[HTML][HTML] C-phycocyanin protects against low fertility by inhibiting reactive oxygen species in aging mice

YJ Li, Z Han, L Ge, CJ Zhou, YF Zhao, DH Wang… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Women over 35 have higher rates of infertility, largely due to deterioration of oocyte quality
characterized by fragmentation, abnormal meiotic spindle-chromosome complexes, and …

The protective effect of C-phycocyanin in male mouse reproductive system

FH Yang, XL Dong, GX Liu, L Teng, L Wang, F Zhu… - Food & function, 2022 - pubs.rsc.org
C-phycocyanin from Spirulina platensis has pharmacological effects such as anti-oxidation,
anti-cancer, anti-inflammatory and anti-atherosclerosis activities as well as liver and kidney …

C-Phycocyanin protects against mitochondrial dysfunction and oxidative stress in parthenogenetic porcine embryos

YJ Niu, W Zhou, J Guo, ZW Nie, KT Shin, NH Kim… - Scientific reports, 2017 - nature.com
C-Phycocyanin (CP) is a biliprotein enriched in blue-green algae that is known to possess
antioxidant, anti-apoptosis, anti-inflammatory, and radical-scavenging properties in somatic …

Phycocyanin Protects against High Glucose High Fat Diet Induced Diabetes in Mice and Participates in AKT and AMPK Signaling

S Hao, F Li, Q Li, Q Yang, W Zhang - Foods, 2022 - mdpi.com
Phycocyanin is a type of marine natural product and functional food additive. Studies have
demonstrated that phycocyanin has potential regulatory effects on glycometabolism, while …

Perinatal administration of C-phycocyanin protects against atherosclerosis in apoE-deficient mice by modulating cholesterol and trimethylamine-N-oxide metabolisms

M Coué, M Croyal, M Habib, B Castellano… - … and Vascular Biology, 2021 - Am Heart Assoc
Objective: Gestational hypercholesterolemia concomitantly with a highly oxidative
environment is associated with higher atherosclerosis in human and animal offspring. This …

Co-enzyme Q10 supplementation rescues cumulus cells dysfunction in a maternal aging model

A Ben-Meir, K Kim, R McQuaid, N Esfandiari, Y Bentov… - Antioxidants, 2019 - mdpi.com
Over the past four decades, due to cultural and social changes, women in the developed
world have significantly delayed childbirth. This trend is even worse for patients who attend …

Cyanidin-3-O-glucoside restores spermatogenic dysfunction in cadmium-exposed pubertal mice via histone ubiquitination and mitigating oxidative damage

X Li, Z Yao, D Yang, X Jiang, J Sun, L Tian, J Hu… - Journal of hazardous …, 2020 - Elsevier
Cadmium (Cd) is an environmental contaminant found in soil, water, and food, and can
cause oxidative stress and male reproductive damage. During puberty, the male …

C-phycocyanin confers protection against oxalate-mediated oxidative stress and mitochondrial dysfunctions in MDCK cells

SM Farooq, NB Boppana, D Asokan, SD Sekaran… - PloS one, 2014 - journals.plos.org
Oxalate toxicity is mediated through generation of reactive oxygen species (ROS) via a
process that is partly dependent on mitochondrial dysfunction. Here, we investigated …

C-type natriuretic peptide improves maternally aged oocytes quality by inhibiting excessive PINK1/Parkin-mediated mitophagy

H Zhang, C Li, Q Liu, J Li, H Wu, R Xu, Y Sun, M Cheng… - Elife, 2023 - elifesciences.org
The overall oocyte quality declines with aging, and this effect is strongly associated with a
higher reactive oxygen species (ROS) level and the resultant oxidative damage. C-type …