[HTML][HTML] Increased frequency of circulating Tc22/Th22 cells and polyfunctional CD38− T cells in HIV-exposed uninfected subjects
Some individuals are resistant to HIV-1 infection despite repeated exposure to the virus,
suggesting the presence of a complex antiviral response. Innate factors like IL-22 exert gut …
suggesting the presence of a complex antiviral response. Innate factors like IL-22 exert gut …
[HTML][HTML] A Low Frequency of IL-17-Producing CD8+ T-Cells Is Associated With Persistent Immune Activation in People Living With HIV Despite HAART-Induced Viral …
F Perdomo-Celis, MG Feria, NA Taborda… - Frontiers in …, 2018 - frontiersin.org
Immune activation is the hallmark of HIV infection, even in patients with highly active anti-
retroviral therapy (HAART)-induced viral suppression. A major cause of immune activation …
retroviral therapy (HAART)-induced viral suppression. A major cause of immune activation …
Long-term non-progressors display a greater number of Th17 cells than HIV-infected typical progressors
Interleukin 17 (IL17) secreting T (Th17) cells play a protective role against bacterial
infections at mucosal surfaces. Recent reports show Th17 cells are depleted in the gut …
infections at mucosal surfaces. Recent reports show Th17 cells are depleted in the gut …
Increased IL-17 and/or IFN-γ producing T-cell subsets in gut mucosa of long-term-treated HIV-1-infected women
Objective: The influence of sex on gut mucosal T-cell response in HIV-1 infection remains
largely unknown. We explored whether the frequencies of interferon-γ and/or IL-17 …
largely unknown. We explored whether the frequencies of interferon-γ and/or IL-17 …
[HTML][HTML] Distribution of functional CD4 and CD8 T cell subsets in blood and rectal mucosal tissues
PK Amancha, CG Ackerley, C Duphare, M Lee, YJ Hu… - Scientific reports, 2019 - nature.com
A better understanding of the distribution and functional capacity of CD4 T helper (Th) and
CD8 T cytotoxic (Tc) cell subsets in the rectal mucosa (RM), a major site for HIV acquisition …
CD8 T cytotoxic (Tc) cell subsets in the rectal mucosa (RM), a major site for HIV acquisition …
[HTML][HTML] A role for mucosal IL-22 production and Th22 cells in HIV-associated mucosal immunopathogenesis
Abstract Interleukin-22 (IL-22) is a cytokine with epithelial reparative and regenerative
properties that is produced by Th22 cells and by other immune cell subsets. Therefore, we …
properties that is produced by Th22 cells and by other immune cell subsets. Therefore, we …
Analysis of Th17 and Tc17 frequencies and antiviral defenses in gut‐associated lymphoid tissue of chronic HIV‐1 positive patients
The complex relationship between both the Th1/Th17 and Tc1/Tc17 axis and innate
defences in the intestinal mucosa during HIV‐1 infection has not been well characterized …
defences in the intestinal mucosa during HIV‐1 infection has not been well characterized …
Loss of IL-17–producing CD8 T Cells during late chronic stage of pathogenic simian immunodeficiency virus infection
Progressive disease caused by pathogenic SIV/HIV infections is marked by systemic
hyperimmune activation, immune dysregulation, and profound depletion of CD4+ T cells in …
hyperimmune activation, immune dysregulation, and profound depletion of CD4+ T cells in …
[HTML][HTML] Dysregulation of IL-17/IL-22 effector functions in blood and gut mucosal gamma delta T cells correlates with increase in circulating leaky gut and inflammatory …
EM Walker, N Slisarenko, GL Gerrets… - Frontiers in …, 2021 - frontiersin.org
HIV-associated inflammation has been implicated in the premature aging and increased risk
of age-associated comorbidities in cART-treated individuals. However, the immune …
of age-associated comorbidities in cART-treated individuals. However, the immune …
HIV-1 infection is characterized by profound depletion of CD161+ Th17 cells and gradual decline in regulatory T cells
A Prendergast, JG Prado, YH Kang, F Chen, LA Riddell… - Aids, 2010 - journals.lww.com
Objective: CD4+ T-cell depletion is central to HIV pathogenesis. However, the relative
impact of HIV on Th17 and regulatory T cell (Treg) subsets remains unclear. CD161+ CD4 …
impact of HIV on Th17 and regulatory T cell (Treg) subsets remains unclear. CD161+ CD4 …