Spinal cord injury (SCI) involves diverse injury responses in different cell types in a
temporally and spatially specific manner. Here, using single-cell transcriptomic analyses …

Spinal cord injury (SCI) leads to severe sensory and motor dysfunction below the lesion.
However, the cellular dynamic responses and heterogeneity across different regions below …

Spinal cord injury (SCI) triggers a complex cascade of molecular and chemical events that
leads to progressive cell loss and tissue damage. 1, 2 Nearly a century of fundamental basic …

Spinal cord injury (SCI) is a devastating neurologic injury with functional deficits. In the acute
phase, which starts at the moment of the injury and extends over the first few days …

Traumatic spinal cord injury (SCI) elicits an acute inflammatory response which comprises
numerous cell populations. It is driven by the immediate response of macrophages and …

Traumatic spinal cord injury (SCI) triggers a neuro-inflammatory response dominated by
tissue-resident microglia and monocyte derived macrophages (MDMs). Since activated …

Traumatic injury to the central nervous system results in the disruption of the blood
brain/spinal barrier, followed by the invasion of cells and other components of the immune …

We have completed the first large-scale gene expression study of acute spinal cord injury
(SCI) in rat. Oligonucleotide microarrays containing 1,200 gene-specific probes were used …

Spinal cord injury (SCI) induces a progressive pathophysiology affecting cell survival and
neurological integrity via complex and evolving molecular cascades whose …

Spinal cord injury (SCI) is a devastating neurological disease without effective treatment. To
generate a comprehensive view of the mechanisms involved in SCI pathology, we applied …