Nanoparticles for oral delivery: Design, evaluation and state-of-the-art
The oral route is a preferred method of drug administration, though achieving effective drug
delivery and minimizing off-target side effects is often challenging. Formulation into …
delivery and minimizing off-target side effects is often challenging. Formulation into …
In vitro and in vivo models for the study of oral delivery of nanoparticles
Oral delivery is an attractive route to deliver therapeutics via nanoparticles due to its ease of
administration and patient compliance. This review discusses laboratory techniques for …
administration and patient compliance. This review discusses laboratory techniques for …
Role of nanoparticle size, shape and surface chemistry in oral drug delivery
A Banerjee, J Qi, R Gogoi, J Wong… - Journal of Controlled …, 2016 - Elsevier
Nanoparticles find intriguing applications in oral drug delivery since they present a large
surface area for interactions with the gastrointestinal tract and can be modified in various …
surface area for interactions with the gastrointestinal tract and can be modified in various …
Oral drug delivery with polymeric nanoparticles: the gastrointestinal mucus barriers
Oral delivery is the most common method for drug administration. However, poor solubility,
stability, and bioavailability of many drugs make achieving therapeutic levels via the …
stability, and bioavailability of many drugs make achieving therapeutic levels via the …
[HTML][HTML] Inorganic nanoparticles for oral drug delivery: opportunities, barriers, and future perspectives
Oral delivery is the preferred route of drug administration due to patient compliance and
convenience. Despite this, nanomedicines have so far primarily been developed for the …
convenience. Despite this, nanomedicines have so far primarily been developed for the …
Polymeric nanoparticle drug delivery technologies for oral delivery applications
EM Pridgen, F Alexis, OC Farokhzad - Expert opinion on drug …, 2015 - Taylor & Francis
Introduction: Many therapeutics are limited to parenteral administration. Oral administration
is a desirable alternative because of the convenience and increased compliance by …
is a desirable alternative because of the convenience and increased compliance by …
Mechanisms of nanoparticle transport across intestinal tissue: an oral delivery perspective
Oral drug administration has been a popular choice due to patient compliance and limited
clinical resources. Orally delivered drugs must circumvent the harsh gastrointestinal (GI) …
clinical resources. Orally delivered drugs must circumvent the harsh gastrointestinal (GI) …
Nanoparticle-based oral drug delivery systems targeting the colon for treatment of ulcerative colitis
Inflammatory bowel disease (IBD), including Crohn's disease (CD) and ulcerative colitis
(UC), is characterized by chronic relapsing inflammation of the gastrointestinal tract. Delivery …
(UC), is characterized by chronic relapsing inflammation of the gastrointestinal tract. Delivery …
Nanoparticles for oral delivery: targeted therapy for inflammatory bowel disease
D Li, M Yang, H Xu, M Zhu, Y Zhang, C Tian… - Journal of Materials …, 2022 - pubs.rsc.org
As a group of chronic and idiopathic gastrointestinal (GI) disorders, inflammatory bowel
disease (IBD) is characterized by recurrent intestinal mucosal inflammation. Oral …
disease (IBD) is characterized by recurrent intestinal mucosal inflammation. Oral …
Polymeric nanoparticle technologies for oral drug delivery
EM Pridgen, F Alexis, OC Farokhzad - Clinical Gastroenterology and …, 2014 - Elsevier
Biologics increasingly are being used for the treatment of many diseases. These treatments
typically require repeated doses administered by injection. Alternate routes of …
typically require repeated doses administered by injection. Alternate routes of …