Our aim was to investigate axonal outgrowth from different tissue models on soft
biomaterials based on hyaluronic acid (HA). We hypothesized that HA-based hydrogels …

Object Therapies that use bioactive materials as replacement extracellular matrices may
hold the potential to mitigate the inhibition of regeneration observed after central nervous …

Damage caused to neural tissue by disease or injury frequently produces a discontinuity in
the nervous system (NS). Such damage generates diverse alterations that are commonly …

Numerous biomaterials based on extracellular matrix-components have been developed. It
was our aim to investigate whether a hyaluronic acid–based hydrogel improves neuronal …

Hyaluronic acid (HA) with one reactive moiety grafted to the backbone is a commonly used
matrix in tissue engineering. The addition of a second orthogonal moiety to the backbone …

A hyaluronic acid (HA)-based extracellular matrix (ECM) platform with independently
tunable stiffness and density of cell-adhesive peptide (RGD, arginine–glycine–aspartic acid) …

Artificial tissue engineering scaffolds can potentially provide support and guidance for the
regrowth of severed axons following nerve injury. In this study, a hybrid biomaterial …

Spinal cord injury (SCI) affects millions of people worldwide, and results in the loss of
neurons and limited recovery of functions. Bone mesenchymal stem cells (BMSCs) and …

Various neural tissue engineering approaches that are under development for applications
ranging from guidance conduits to cell-based therapies rely on the ability to encapsulate …

Objective: To develop a clinically relevant injectable hydrogel derived from decellularized
porcine peripheral nerves and with mechanical properties comparable to native central …