Overcoming the PEG-addiction: well-defined alternatives to PEG, from structure–property relationships to better defined therapeutics

M Barz, R Luxenhofer, R Zentel, MJ Vicent - Polymer Chemistry, 2011 - pubs.rsc.org
Synthetic methods in polymer chemistry have evolved tremendously during the last decade.
Nowadays more and more attention is devoted to the application of those tools in the …

Chemistry routes for copolymer synthesis containing PEG for targeting, imaging, and drug delivery purposes

K Rahme, N Dagher - Pharmaceutics, 2019 - mdpi.com
Polyethylene glycol (PEG) is one of the most frequently used polymers for coating
nanocarriers to enhance their biocompatibility, hydrophilicity, stability, and biodegradability …

Poly (ethylene glycol) in drug delivery: pros and cons as well as potential alternatives

K Knop, R Hoogenboom, D Fischer… - Angewandte chemie …, 2010 - Wiley Online Library
Abstract Poly (ethylene glycol)(PEG) is the most used polymer and also the gold standard for
stealth polymers in the emerging field of polymer‐based drug delivery. The properties that …

Multifunctional Poly (ethylene glycol) s

B Obermeier, F Wurm, C Mangold… - Angewandte Chemie …, 2011 - Wiley Online Library
In the rapidly evolving multidisciplinary field of polymer therapeutics, tailored polymer
structures represent the key constituent to explore and harvest the potential of bioactive …

PEG-PCL-based nanomedicines: A biodegradable drug delivery system and its application

P Grossen, D Witzigmann, S Sieber… - Journal of Controlled …, 2017 - Elsevier
The lack of efficient therapeutic options for many severe disorders including cancer spurs
demand for improved drug delivery technologies. Nanoscale drug delivery systems based …

[PDF][PDF] Recent applications of polyethylene glycols (PEGs) and PEG derivatives

D Hutanu, MD Frishberg, L Guo, CC Darie - Mod. Chem. Appl, 2014 - jenkemusa.com
Numerous applications of polyethylene glycol derived polymers (PEGs) have been reported
in the scientific literature for many years. With increasing experience and comfort by …

Polymerization of oligo (ethylene glycol)(meth) acrylates: Toward new generations of smart biocompatible materials

JF Lutz - Journal of Polymer Science Part A: Polymer Chemistry, 2008 - Wiley Online Library
Monomers composed of a (meth) acrylate moiety connected to a short poly (ethylene) glycol
(PEG) chain are versatile building‐blocks for the preparation of “smart” biorelevant …

Functional polymers as therapeutic agents: concept to market place

PK Dhal, SC Polomoscanik, LZ Avila… - Advanced drug delivery …, 2009 - Elsevier
Biologically active synthetic polymers have received considerable scientific interest and
attention in recent years for their potential as promising novel therapeutic agents to treat …

PEGylated polymers for medicine: from conjugation to self-assembled systems

MJ Joralemon, S McRae, T Emrick - Chemical Communications, 2010 - pubs.rsc.org
Synthetic polymers have transformed society in many areas of science and technology,
including recent breakthroughs in medicine. Synthetic polymers now offer unique and …

Poly (ethylene glycol) alternatives in biomedical applications

X Yao, C Qi, C Sun, F Huo, X Jiang - Nano Today, 2023 - Elsevier
Abstract Poly (ethylene glycol)(PEG) as gold standard has been extensively conjugated to
diagnostic and therapeutic agents or decorated on the surface of nanoplatforms, which is …