A range of antitumor agents for cancer treatment is available; however, they show low
specificity, which often limit their use. Recently, we have reported the preparation of folate …

Paclitaxel (PTX) is a microtubule-stabilizing agent widely used to treat breast cancer.
Nevertheless, the low solubility of the drug and the side effects of commercial formulations …

Background The purpose of this study was to develop folate-poly (PEG-cyanoacrylate-co-
cholesteryl cyanoacrylate)(FA-PEG-PCHL)-modified freeze-dried liposomes for targeted …

A novel liposomal formulation of paclitaxel targeting the folate receptor (FR) was
synthesized and characterized. This formulation was designed to overcome vehicle toxicity …

The purpose of this study was to investigate the in vivo distribution and antitumor activity of
irinotecan (camptothecin (CPT)-11)-loaded folate-targeted liposome (F-Lip) in tumor-bearing …

In this paper, a folate-PEG coated polymeric liposome (FPL) formed from octadecyl-
quaternized lysine modified chitosan (OQLCS) and cholesterol has been prepared …

Background: Gemcitabine (GEM) is found effective in the treatment of many solid tumors.
However, its use is restricted due to its small circulation half-life, fast metabolism and low …

Cancer is the major burden of disease worldwide. The folate receptor, as a specific tumor
target, is over-expressed in many types of cancer including ovarian carcinomas, breast …

Doxorubicin (DOX) loaded liposomes have been used and studied in the last decades due
to the significant decrease in DOX induced cardiac and systemic toxicity relative to …

A novel liposomal formulation of docetaxel targeting the folate receptor (FR) was
synthesized and characterized. Liposomal formulations are less toxic and can provide …