Creatine monohydrate is actively being researched for its antidepressant effects, yet little is
known about the link between dietary creatine and depression risk. This study examines the …

The potential role of metabolic impairments in the pathophysiology of depression is
motivating researchers to evaluate the treatment efficacy of creatine, a naturally occurring …

Depressed mood, which can occur in the context of major depressive disorder, bipolar
disorder, and other conditions, represents a serious threat to public health and wellness …

Creatine is a non-proteinogenic amino acid available from various animal-based foods or
synthesized endogenously in the human body. A number of recent population-based studies …

Objective: Depression among methamphetamine users is more prevalent in females than
males, but gender-specific treatment options for this comorbidity have not been described …

Impairments in bioenergetic function, cellular resiliency, and structural plasticity are
associated with the pathogenesis of mood disorders. Preliminary evidence suggests that …

Athletes, body builders, and military personnel use dietary creatine as an ergogenic aid to
boost physical performance in sports involving short bursts of high-intensity muscle activity …

The creatine/phosphocreatine/creatine kinase circuit is instrumental in regulating high-
energy phosphate metabolism, and the maintenance of cellular energy turnover. The …

Context From an energy perspective, the brain is very metabolically demanding. It is well
documented that creatine plays a key role in brain bioenergetics. There is some evidence …

It has been hypothesized that dietary creatine could influence cognitive performance by
increasing brain creatine in developing individuals. This double-blind, randomized, placebo …