Cathepsin B is a lysosomal enzyme thought to be involved in tumour cell invasion and
metastasis. This study was designed to investigate the presence of a known leucine to …

Human cathepsin B (CTSB) is a proteolytic enzyme implicated in tumor invasion and
metastasis. We describe a PCR-based polymorphic marker for this gene comprising two …

Background/Aim: Cathepsin G (CTSG) has been identified as an inhibitor of breast, bladder,
and colorectal cancers. The G allele of the N125S (A/G, rs45567233) functional …

Single nucleotide polymorphism (SNP) in some genes is a candidate for having or
developing a cancer. Cathepsin B (CTSB) is considered to be the biomarker of cancers. The …

BACKGROUND: Genetic polymorphisms are believed to represent a key aspect of
predisposition to gastric cancer (GC). Therefore, considering the important role of Cathepsin …

Background: Japanese-American (JA) men who have immigrated to the USA and acquired
the Western lifestyle usually have more invasive prostate cancer (PCa) than native …

Background: Increased incidence and mortality of prostate cancer (PCa) suggest that US
African-American men have more invasive cancer than Caucasian men. Invasive PCa …

Cathepsin D (CTSD) is a lysosomal protease involved in the pathogenesis of several
diseases such as breast cancer and possibly Alzheimer's disease (AD). Previous findings …

BACKGROUND Evidence is accumulating that several proteases are involved in prostate
cancer progression. A locus which is often amplified in prostate cancer is the chromosomal …

Background: Cathepsin B has been shown to play an important role in invasion and
metastasis of prostate cancer. The objective of this study was to determine whether serum …