Mitophagy, mitochondrial homeostasis, and cell fate

K Ma, G Chen, W Li, O Kepp, Y Zhu… - Frontiers in cell and …, 2020 - frontiersin.org
Mitochondria are highly plastic and dynamic organelles that have graded responses to the
changing cellular, environmental, and developmental cues. Mitochondria undergo constant …

Molecular mechanisms and regulation of mammalian mitophagy

V Choubey, A Zeb, A Kaasik - Cells, 2021 - mdpi.com
Mitochondria in the cell are the center for energy production, essential biomolecule
synthesis, and cell fate determination. Moreover, the mitochondrial functional versatility …

The role of mitophagy in regulating cell death

S Li, J Zhang, C Liu, Q Wang, J Yan… - Oxidative Medicine …, 2021 - Wiley Online Library
Mitochondria are multifaceted organelles that serve to power critical cellular functions,
including act as power generators of the cell, buffer cytosolic calcium overload, production of …

Mitophagy: a complex mechanism of mitochondrial removal

I Novak - Antioxidants & redox signaling, 2012 - liebertpub.com
Significance: Mitochondrial dynamics and turnover are crucial for cellular homeostasis and
differentiation. The removal of damaged mitochondria that could contribute to cellular …

[HTML][HTML] Mitochondrial quality control as a key determinant of cell survival

L Sedlackova, VI Korolchuk - … et Biophysica Acta (BBA)-Molecular Cell …, 2019 - Elsevier
Mitochondria are the energy producing dynamic double-membraned organelles essential
for cellular and organismal survival. A multitude of intra-and extra-cellular signals involved in …

Molecular mechanisms and physiological functions of mitophagy

M Onishi, K Yamano, M Sato, N Matsuda… - The EMBO …, 2021 - embopress.org
Degradation of mitochondria via a selective form of autophagy, named mitophagy, is a
fundamental mechanism conserved from yeast to humans that regulates mitochondrial …

[HTML][HTML] Mitochondrial degradation: Mitophagy and beyond

L Uoselis, TN Nguyen, M Lazarou - Molecular cell, 2023 - cell.com
Mitochondria are central hubs of cellular metabolism that also play key roles in signaling
and disease. It is therefore fundamentally important that mitochondrial quality and activity …

Mitochondria and cell signalling

SWG Tait, DR Green - Journal of cell science, 2012 - journals.biologists.com
Mitochondria have long been considered as crucial organelles, primarily for their roles in
biosynthetic reactions such as ATP synthesis. However, it is becoming increasingly apparent …

Mitochondria as cellular and organismal signaling hubs

K Shen, CL Pender, R Bar-Ziv, H Zhang… - Annual review of cell …, 2022 - annualreviews.org
Mitochondria are traditionally known as the powerhouse of the cell, but their functions
extend far beyond energy production. They are vital in cellular and organismal pathways …

Evolving and expanding the roles of mitophagy as a homeostatic and pathogenic process

ÅB Gustafsson, GW Dorn - Physiological reviews, 2019 - journals.physiology.org
The central functions fulfilled by mitochondria as both energy generators essential for tissue
homeostasis and gateways to programmed apoptotic and necrotic cell death mandate tight …