[图书][B] Perinatal Epigenetic Signature of Autism Spectrum Disorder

Y Zhu - 2021 - search.proquest.com
Abstract Autism Spectrum Disorder (ASD) is a polygenic neurodevelopmental disorder that
includes deficits in social communication and repetitive behaviors. Most ASD cases are …

Epigenomic signatures reveal mechanistic clues and predictive markers for autism spectrum disorder

JM LaSalle - Molecular psychiatry, 2023 - nature.com
Autism spectrum disorder (ASD) comprises a heterogeneous group of neurodevelopmental
outcomes in children with a commonality in deficits in social communication and language …

[PDF][PDF] Placental methylome reveals a 22q13. 33 brain regulatory gene locus associated with autism

DC Soto, MY Dennis, KS Benke, KM Bakulski… - 2022 - genomebiology.biomedcentral.com
Background: Autism spectrum disorder (ASD) involves complex genetics interacting with the
perinatal environment, complicating the discovery of common genetic risk. The epigenetic …

Placental DNA methylation changes and the early prediction of autism in full-term newborns

RO Bahado-Singh, S Vishweswaraiah, B Aydas… - PLoS …, 2021 - journals.plos.org
Autism spectrum disorder (ASD) is associated with abnormal brain development during fetal
life. Overall, increasing evidence indicates an important role of epigenetic dysfunction in …

[HTML][HTML] The promise of DNA methylation in understanding multigenerational factors in autism spectrum disorders

JS Mouat, JM LaSalle - Frontiers in Genetics, 2022 - frontiersin.org
Autism spectrum disorder (ASD) is a group of neurodevelopmental disorders characterized
by impairments in social reciprocity and communication, restrictive interests, and repetitive …

Placental DNA methylation levels at CYP2E1 and IRS2 are associated with child outcome in a prospective autism study

Y Zhu, CE Mordaunt, DH Yasui… - Human molecular …, 2019 - academic.oup.com
DNA methylation acts at the interface of genetic and environmental factors relevant for
autism spectrum disorder (ASD). Placenta, normally discarded at birth, is a potentially rich …

Placental methylome reveals a 22q13. 33 brain regulatory gene locus associated with autism

Y Zhu, JA Gomez, BI Laufer, CE Mordaunt, JS Mouat… - Genome biology, 2022 - Springer
Background Autism spectrum disorder (ASD) involves complex genetics interacting with the
perinatal environment, complicating the discovery of common genetic risk. The epigenetic …

Placental methylome analysis from a prospective autism study

DI Schroeder, RJ Schmidt, FK Crary-Dooley… - Molecular autism, 2016 - Springer
Background Autism spectrum disorders (ASD) are increasingly prevalent
neurodevelopmental disorders that are behaviorally diagnosed in early childhood. Most …

Genetics of autism spectrum disorders and future direction

Y Yasuda, J Matsumoto, K Miura… - Journal of Human …, 2023 - nature.com
Autism spectrum disorders (ASDs) have been increasing in prevalence. ASD is a complex
human genetic disorder with high heredity and involves interactions between genes and the …

[HTML][HTML] Autism-associated DNA methylation at birth from multiple tissues is enriched for autism genes in the early autism risk longitudinal investigation

KM Bakulski, JF Dou, JI Feinberg, MT Aung… - Frontiers in Molecular …, 2021 - frontiersin.org
Background: Pregnancy measures of DNA methylation, an epigenetic mark, may be
associated with autism spectrum disorder (ASD) development in children. Few ASD studies …