Systematic review: bile acids and intestinal inflammation‐luminal aggressors or regulators of mucosal defence?

P Pavlidis, N Powell, RP Vincent… - Alimentary …, 2015 - Wiley Online Library
Background Inflammatory bowel diseases (IBD), comprising Crohn's disease and ulcerative
colitis (UC), are chronic conditions attributed to an aberrant immune response to luminal …

Bile acids as inflammatory mediators and modulators of intestinal permeability

N Calzadilla, SM Comiskey, PK Dudeja… - Frontiers in …, 2022 - frontiersin.org
Bile acids are critical for the digestion and absorption of lipids and fat-soluble vitamins;
however, evidence continues to emerge supporting additional roles for bile acids as …

Bile acid signaling in inflammatory bowel disease

MA Bromke, M Krzystek-Korpacka - International Journal of Molecular …, 2021 - mdpi.com
Inflammatory bowel disease is a chronic, idiopathic and complex condition, which most often
manifests itself in the form of ulcerative colitis or Crohn's disease. Both forms are associated …

Bile acid-related regulation of mucosal inflammation and intestinal motility: from pathogenesis to therapeutic application in IBD and microscopic colitis

F Di Vincenzo, P Puca, LR Lopetuso, V Petito, L Masi… - Nutrients, 2022 - mdpi.com
Inflammatory bowel diseases (IBD) and microscopic colitis are chronic immune-mediated
inflammatory disorders that affect the gastroenterological tract and arise from a complex …

Critical roles of bile acids in regulating intestinal mucosal immune responses

R Sun, C Xu, B Feng, X Gao… - Therapeutic Advances in …, 2021 - journals.sagepub.com
Bile acids are a class of cholesterol derivatives that have been known for a long time for their
critical roles in facilitating the digestion and absorption of lipid from the daily diet. The …

The emerging role of bile acids in the pathogenesis of inflammatory bowel disease

JP Thomas, D Modos, SM Rushbrook… - Frontiers in …, 2022 - frontiersin.org
Inflammatory bowel disease (IBD) is a chronic immune-mediated inflammatory disorder of
the gastrointestinal tract that arises due to complex interactions between host genetic risk …

[HTML][HTML] Emerging roles of bile acids in mucosal immunity and inflammation

ML Chen, K Takeda, MS Sundrud - Mucosal Immunology, 2019 - Elsevier
Bile acids are cholesterol-derived surfactants that circulate actively between the liver and
ileum and that are classically recognized for emulsifying dietary lipids to facilitate absorption …

Interactions between diet, bile acid metabolism, gut microbiota, and inflammatory bowel diseases

S Devkota, EB Chang - Digestive diseases, 2015 - karger.com
The composite human gut microbiomes of Western populations have changed over the past
century, brought on by new environmental triggers that often have a negative impact on …

The interaction of bile acids and gut inflammation influences the pathogenesis of inflammatory bowel disease

A Di Ciaula, L Bonfrate, M Khalil… - Internal and Emergency …, 2023 - Springer
Bile acids (BA) are amphipathic molecules originating from cholesterol in the liver and from
microbiota-driven biotransformation in the colon. In the gut, BA play a key role in fat …

Bile acids: key players in inflammatory bowel diseases?

A Kriaa, V Mariaule, A Jablaoui, S Rhimi, H Mkaouar… - Cells, 2022 - mdpi.com
Inflammatory bowel diseases (IBDs) have emerged as a public health problem worldwide
with a limited number of efficient therapeutic options despite advances in medical therapy …