Precise Capture and Dynamic Release of Circulating Liver Cancer Cells with Dual‐Histidine‐Based Cell Imprinted Hydrogels

W Sun, X You, X Zhao, X Zhang, C Yang… - Advanced …, 2024 - Wiley Online Library
Circulating tumor cells (CTCs) detection presents significant advantages in diagnosing liver
cancer due to its noninvasiveness, real‐time monitoring, and dynamic tracking. However …

Highly Integrated Cell-Imprinted Biomimetic Interface for All-in-One Diagnosis of Heterogeneous Circulating Tumor Cells

S Gao, S Chen, Y Liu, H Mao, Q Lu - ACS Applied Materials & …, 2021 - ACS Publications
Single-cell capture and in situ analysis of circulating tumor cells (CTCs) in blood are of great
significance for early cancer diagnosis, prognosis, and individualized treatment. However …

Multi-DNA-Modified Double-Network Hydrogel with Customized Microstructure: A Novel System for Living Circulating Tumor Cells Capture and Real-Time Detection

D Chen, Y Li, X Liu, Y Zhao, T Ren, J Guo… - … Applied Materials & …, 2024 - ACS Publications
The precise and effective isolation of living circulating tumor cells (CTCs) from peripheral
blood, followed by their real-time monitoring, is crucial for diagnosing cancer patients. In this …

Antibody‐free hydrogel with the synergistic effect of cell imprinting and boronate affinity: toward the selective capture and release of undamaged circulating tumor cells

L Liu, C Dong, X Li, S Li, B Ma, B Zhao, X Li, Z Liang… - Small, 2020 - Wiley Online Library
The selective and highly efficient capture of circulating tumor cells (CTCs) from blood and
their subsequent release without damage are very important for the early diagnosis of …

[HTML][HTML] Thermo-responsive imprinted hydrogel with switchable sialic acid recognition for selective cancer cell isolation from blood

Y Ma, Y Yin, L Ni, H Miao, Y Wang, C Pan, X Tian… - Bioactive Materials, 2021 - Elsevier
In this work, a sialic acid (SA)-imprinted thermo-responsive hydrogel layer was prepared for
selective capture and release of cancer cells. The SA-imprinting process was performed at …

Biospecific monolayer coating for multivalent capture of circulating tumor cells with high sensitivity

J Chen, L Yu, Y Li, JL Cuellar‐Camacho… - Advanced Functional …, 2019 - Wiley Online Library
The isolation and detection of rare circulating tumor cells (CTCs) from patient peripheral
blood can help to monitor the metastatic spread of carcinoma and evaluate therapeutic …

Improving performance of cell imprinted PDMS by integrating boronate affinity and local post-imprinting modification for selective capture of circulating tumor cells from …

Y Sun, Y Luo, L Sun, XR Wang, LW Chen… - Biosensors and …, 2023 - Elsevier
Efficient capture of circulating tumor cells (CTCs) from cancer patients is an important
technique that may promote early diagnosis and prognosis monitoring of cancer. However …

Polyglycerol‐Based Biomedical Matrix for Immunomagnetic Circulating Tumor Cell Isolation and Their Expansion into Tumor Spheroids for Drug Screening

P Tang, B Thongrom, S Arora… - Advanced Healthcare …, 2023 - Wiley Online Library
Circulating tumor cells (CTCs) are established as distinct cancer biomarkers for diagnosis,
as preclinical models, and therapeutic targets. Their use as preclinical models is limited …

Engineered Leukocyte Biomimetic Colorimetric Sensor Enables High-Efficient Detection of Tumor Cells Based on Bioorthogonal Chemistry

M Li, L Jia, A Zhu, J Li, J Li, X Liu… - ACS Applied Materials & …, 2024 - ACS Publications
Accurate detection of heterogeneous circulating tumor cells (CTCs) is critical as they can
make tumor cells more aggressive, drug-resistant, and metastasizing. Although the …

[HTML][HTML] Affinity-enhanced CTC-capturing hydrogel microparticles fabricated by degassed Mold lithography

NJ Lee, S Maeng, HU Kim, YH Roh, C Hwang… - Journal of Clinical …, 2020 - mdpi.com
Technologies for the detection and isolation of circulating tumor cells (CTCs) are essential in
liquid biopsy, a minimally invasive technique for early diagnosis and medical intervention in …