An update on T-2 toxin and its modified forms: Metabolism, immunotoxicity mechanism, and human exposure assessment

Q Wu, Z Qin, K Kuca, L You, Y Zhao, A Liu… - Archives of …, 2020 - Springer
T-2 toxin is the most toxic trichothecene mycotoxin, and it exerts potent toxic effects,
including immunotoxicity, neurotoxicity, and reproductive toxicity. Recently, several novel …

T-2 toxin, a trichothecene mycotoxin: review of toxicity, metabolism, and analytical methods

Y Li, Z Wang, RC Beier, J Shen, DD Smet… - Journal of agricultural …, 2011 - ACS Publications
This review focuses on the toxicity and metabolism of T-2 toxin and analytical methods used
for the determination of T-2 toxin. Among the naturally occurring trichothecenes in food and …

T-2 toxin metabolism and its hepatotoxicity: New insights on the molecular mechanism and detoxification

W Song, Y Wang, T Huang, Y Liu, F Chen, Y Chen… - Environmental …, 2023 - Elsevier
T-2 toxin, a type A trichothecene, is a secondary metabolite produced by Fusarium poae,
Fusarium sporotrichioides, and Fusarium tricinctum. As the most toxic trichothecenes, T-2 …

[HTML][HTML] T-2 and HT-2 Toxins: Toxicity, occurrence and analysis: A review

J Meneely, B Greer, O Kolawole, C Elliott - Toxins, 2023 - mdpi.com
One of the major classes of mycotoxins posing serious hazards to humans and animals and
potentially causing severe economic impact to the cereal industry are the trichothecenes …

Metabolism and cytotoxic effects of T-2 toxin and its metabolites on human cells in primary culture

M Königs, D Mulac, G Schwerdt, M Gekle, HU Humpf - Toxicology, 2009 - Elsevier
T-2 toxin belongs to the large group of trichothecene mycotoxins synthesized by various
Fusarium molds which can infect raw agriculture materials. Among the trichothecenes, T-2 …

Brain damage and neurological symptoms induced by T-2 toxin in rat brain

P Guo, A Liu, D Huang, Q Wu, Z Fatima, Y Tao… - Toxicology letters, 2018 - Elsevier
T-2 toxin, a trichothecene mycotoxin, is a common contaminant in food and animal feed, and
is also present in processed cereal products. The most common route of T-2 toxin exposure …

Review of the reproductive toxicity of T-2 toxin

X Yang, P Liu, Y Cui, B Xiao, M Liu… - Journal of agricultural …, 2020 - ACS Publications
T-2 toxin, an inevitable environmental pollutant, is the most toxic type A trichothecene
mycotoxin. Reproductive disruption is a key adverse effect of T-2 toxin. Herein, this paper …

[HTML][HTML] T-2 toxin—The most toxic trichothecene mycotoxin: Metabolism, toxicity, and decontamination strategies

E Janik, M Niemcewicz, M Podogrocki, M Ceremuga… - Molecules, 2021 - mdpi.com
Among trichothecenes, T-2 toxin is the most toxic fungal secondary metabolite produced by
different Fusarium species. Moreover, T-2 is the most common cause of poisoning that …

[HTML][HTML] T-2 mycotoxin: toxicological effects and decontamination strategies

M Adhikari, B Negi, N Kaushik, A Adhikari… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Mycotoxins are highly diverse secondary metabolites produced in nature by a wide variety of
fungus which causes food contamination, resulting in mycotoxicosis in animals and humans …

Individual and combined cytotoxic effects of T-2 toxin and its four metabolites on porcine Leydig cells

A Ling, L Sun, W Guo, S Sun, J Yang, Z Zhao - Food and Chemical …, 2020 - Elsevier
T-2 toxin, one of the most toxic mycotoxins, is commonly presented along with its
metabolites, HT-2 toxin, neosolaniol (NEO), T-2 triol, and T-2 tetraol in foodstuff and feed …