The increasing integration of genomics into routine clinical diagnostics requires reliable
computational tools to identify determinants of antimicrobial resistance (AMR) from whole …

ABSTRACT The CDC's Emerging Infections Program (EIP) conducted population-and
laboratory-based surveillance of US carbapenem-resistant Pseudomonas aeruginosa …

Carbapenem resistance is a major concern in the management of antibiotic-resistant
Pseudomonas aeruginosa infections. The direct prediction of carbapenem-resistant …

Objectives Alteration of the porin-encoding gene oprD by insertion sequences (ISs) is one
mechanism conferring carbapenem resistance in Pseudomonas aeruginosa. Here we …

Background Antimicrobial resistance (AMR) is an intensifying threat that requires urgent
mitigation to avoid a post-antibiotic era. The bacterial pathogen, Pseudomonas aeruginosa …

Infections by Pseudomonas aeruginosa are difficult to cure due to its high intrinsic and
acquired antibiotic resistance. Once colonized the human host, and thanks to antibiotic …

Antimicrobial resistance (AMR) is now recognized as a global threat to human health. The
accessibility of microbial whole-genome sequencing offers an invaluable opportunity for …

Abstract Objectives Pan-susceptible Pseudomonas aeruginosa (PSPA) clinical isolates
carrying an OprD with loop 7 shortening (the group-1A allele) were found to rapidly develop …

Objective Pseudomonas aeruginosa has strong drug resistance and can tolerate a variety of
antibiotics, which is a major problem in the management of antibiotic-resistant infections …

Carbapenem resistance in Pseudomonas aeruginosa is increasing globally, and
surveillance to define the mechanisms of such resistance in low-and middle-income …