Human cytomegalovirus (HCMV) can establish both nonproductive (latent) and productive
(lytic) infections. Many of the proteins expressed during these phases of infection could be …

Human cytomegalovirus (HCMV) infection is largely asymptomatic in the immunocompetent
host, but remains a major cause of morbidity in immunosuppressed individuals. Using the …

ABSTRACT CD8+ T cells specific for pp65, IE1, and IE2 are present at high frequencies in
human cytomegalovirus (HCMV)-seropositive individuals, and these have been shown to …

Human cytomegalovirus (HCMV) infections of immunocompetent hosts are characterized by
a dynamic, life-long interaction in which host immune responses, particularly of T cells …

While CD8+ T cells specific for human cytomegalovirus (HCMV) have been extensively
studied in both healthy HCMV seropositive carriers and patients undergoing …

Human cytomegalovirus (HCMV) infection and periodic reactivation are generally well
controlled by the HCMV-specific T cell response in healthy people. While the CD8+ T cell …

CD8+ T cells are key effectors of the immune response against human cytomegalovirus
(HCMV). A number of HCMV-derived CD8+ T cell epitopes are known. Using epitope …

Recombinant modified vaccinia Ankara-and peptide-based IFN-γ ELISPOT assays were
used to detect and measure human CMV (HCMV)-specific CD8+ T cell responses to the …

A large percentage of healthy individuals (50–90%) is chronically infected with
Cytomegalovirus (CMV). Over the past few years, several techniques were developed in …

Although cytomegalovirus (CMV) expresses proteins that interfere with antigen presentation
by class I major histocompatibility complex (MHC) molecules, CD8+ cytotoxic T cells (CTLs) …