Glucocorticosteroids: current and future directions
PJ Barnes - British journal of pharmacology, 2011 - Wiley Online Library
Glucocorticoids are the most effective anti‐inflammatory therapy for asthma yet are relatively
ineffective in chronic obstructive pulmonary disease. Glucocorticoids suppress inflammation …
ineffective in chronic obstructive pulmonary disease. Glucocorticoids suppress inflammation …
How corticosteroids control inflammation: quintiles prize lecture 2005
PJ Barnes - British journal of pharmacology, 2006 - Wiley Online Library
Corticosteroids are the most effective anti‐inflammatory therapy for many chronic
inflammatory diseases, such as asthma but are relatively ineffective in other diseases such …
inflammatory diseases, such as asthma but are relatively ineffective in other diseases such …
Mechanisms and resistance in glucocorticoid control of inflammation
PJ Barnes - The Journal of steroid biochemistry and molecular …, 2010 - Elsevier
Glucocorticoids are the most effective anti-inflammatory therapy for many chronic
inflammatory and immune diseases, such as asthma, but are relatively ineffective in other …
inflammatory and immune diseases, such as asthma, but are relatively ineffective in other …
Corticosteroids: the drugs to beat
PJ Barnes - European journal of pharmacology, 2006 - Elsevier
Corticosteroids are the most effective anti-inflammatory therapy for asthma and other chronic
inflammatory and immune diseases. Recently new insights have been gained into the …
inflammatory and immune diseases. Recently new insights have been gained into the …
Glucocorticoids: mechanisms of action and anti‐inflammatory potential in asthma
VHJ Van Der Velden - Mediators of inflammation, 1998 - Wiley Online Library
Glucocorticoids are potent inhibitors of inflammatory processes and are widely used in the
treatment of asthma. The anti‐inflammatory effects are mediated either by direct binding of …
treatment of asthma. The anti‐inflammatory effects are mediated either by direct binding of …
Molecular mechanisms and cellular effects of glucocorticosteroids
PJ Barnes - Immunology and Allergy Clinics, 2005 - immunology.theclinics.com
Glucocorticosteroids (GCSs) are widely used to treat various inflammatory and immune
diseases. The most common use of GCSs today is in the treatment of asthma and other …
diseases. The most common use of GCSs today is in the treatment of asthma and other …
Glucocorticoid-regulated transcription factors
IM Adcock - Pulmonary pharmacology & therapeutics, 2001 - Elsevier
Glucocorticoids are the most effective antiinflammatory drugs used in the treatment of
asthma. They act by binding to a specific receptor (GR) that, upon activation, translocates to …
asthma. They act by binding to a specific receptor (GR) that, upon activation, translocates to …
[HTML][HTML] Why do some asthma patients respond poorly to glucocorticoid therapy?
I Henderson, E Caiazzo, C McSharry, TJ Guzik… - Pharmacological …, 2020 - Elsevier
Glucocorticosteroids are the first-line therapy for controlling airway inflammation in asthma.
They bind intracellular glucocorticoid receptors to trigger increased expression of anti …
They bind intracellular glucocorticoid receptors to trigger increased expression of anti …
Anti-inflammatory actions of glucocorticoids: molecular mechanisms
PJ Barnes - Clinical science, 1998 - portlandpress.com
1. Glucocorticoids are widely used for the suppression of inflammation in chronic
inflammatory diseases such as asthma, rheumatoid arthritis, inflammatory bowel disease …
inflammatory diseases such as asthma, rheumatoid arthritis, inflammatory bowel disease …
Update on glucocorticoid action and resistance
Extensive development of inhaled and oral glucocorticoids has resulted in highly potent
molecules that have been optimized to target activity to the lung and minimize systemic …
molecules that have been optimized to target activity to the lung and minimize systemic …