[HTML][HTML] Midbrain dopaminergic neurons: a review of the molecular circuitry that regulates their development

SV Hegarty, AM Sullivan, GW O'keeffe - Developmental biology, 2013 - Elsevier
Dopaminergic (DA) neurons of the ventral midbrain (VM) play vital roles in the regulation of
voluntary movement, emotion and reward. They are divided into the A8, A9 and A10 …

Genetic networks controlling the development of midbrain dopaminergic neurons

N Prakash, W Wurst - The Journal of physiology, 2006 - Wiley Online Library
Recent data have substantially advanced our understanding of midbrain dopaminergic
neuron development. Firstly, a Wnt1‐regulated genetic network, including Otx2 and Nkx2‐2 …

Genetic control of midbrain dopaminergic neuron development

S Blaess, SL Ang - Wiley Interdisciplinary Reviews …, 2015 - Wiley Online Library
Midbrain dopaminergic neurons are involved in regulating motor control, reward behavior,
and cognition. Degeneration or dysfunction of midbrain dopaminergic neurons is implicated …

[HTML][HTML] Midbrain dopamine neuron differentiation: factors and fates

A Abeliovich, R Hammond - Developmental biology, 2007 - Elsevier
Dopaminergic neurons in the midbrain (mDNs) play a central role in the regulation of
voluntary movement as well as other complex behaviors, and their loss is associated with …

Transcriptional control of midbrain dopaminergic neuron development

SL Ang - 2006 - journals.biologists.com
Although loss of midbrain dopaminergic neurons is associated with one of the most common
human neurological disorders, Parkinson's disease, little is known about the specification of …

Midbrain dopaminergic neuron fate specification: Of mice and embryonic stem cells

E Gale, M Li - Molecular brain, 2008 - Springer
The midbrain dopaminergic (mDA) neurons of the substantia nigra and the ventral tegmental
area play a fundamental role in the control of voluntary movement and the regulation of …

How to make a midbrain dopaminergic neuron

E Arenas, M Denham, JC Villaescusa - Development, 2015 - journals.biologists.com
Midbrain dopaminergic (mDA) neuron development has been an intense area of research
during recent years. This is due in part to a growing interest in regenerative medicine and …

Midbrain Dopaminergic Neuron Development at the Single Cell Level: In vivo and in Stem Cells

ES Ásgrímsdóttir, E Arenas - Frontiers in Cell and Developmental …, 2020 - frontiersin.org
Parkinson's disease (PD) is a progressive neurodegenerative disorder that predominantly
affects dopaminergic (DA) neurons of the substantia nigra. Current treatment options for PD …

Development, wiring and function of dopamine neuron subtypes

O Garritsen, EY van Battum, LM Grossouw… - Nature Reviews …, 2023 - nature.com
The midbrain dopamine (mDA) system is composed of molecularly and functionally distinct
neuron subtypes that mediate specific behaviours and are linked to various brain diseases …

Development and differentiation of midbrain dopaminergic neuron: From bench to bedside

M Wang, KH Ling, JJ Tan, CB Lu - Cells, 2020 - mdpi.com
Parkinson's Disease (PD) is a neurodegenerative disorder affecting the motor system. It is
primarily due to substantial loss of midbrain dopamine (mDA) neurons in the substantia …