Neuroinflammation plays a pivotal role in Alzheimer's disease (AD) and Parkinson's disease
(PD), the leading causes of dementia. These neurological disorders are characterized by the …

Increased reactive oxygen species production and oxidative stress have been implicated in
the pathogenesis of numerous neurodegenerative conditions including among others …

Oxidative stress is considered as one of the pathogenesis of Alzheimer's disease (AD) and
plays an important role in the occurrence and development of AD. Nuclear factor erythroid 2 …

Parkinson's disease (PD) is the second most common progressive neurodegenerative
disorder with increased oxidative stress as central component. Till date, treatments related to …

The nuclear factor erythroid-derived 2-related factor 2 (NFE2L2/NRF2) is a master
transcription factor that regulates oxidative stress-related genes containing the antioxidant …

The increase in human life expectancy has become a challenge to reduce the deleterious
consequences of aging. Nowadays, an increasing number of the population suffer from age …

Neurodegenerative diseases (NDDs) are predicted to be the biggest health concern in this
century and the second leading cause of death by 2050. The main risk factor of these …

Recently, growing evidence has demonstrated that nuclear factor erythroid 2-related factor 2
(Nrf2) is a pivotal regulator of endogenous defense systems that function via the activation of …

A failure in redox homeostasis is a common hallmark of Alzheimer's Disease (AD) and
Parkinson's Disease (PD), two age-dependent neurodegenerative disorders (NDD), causing …

Alzheimer's disease (AD) is the most common cause of dementia in the general population
and, to date, constitutes a major therapeutic challenge. In the pathogenesis of AD …