Two complementary strategies to improve cell engraftment in mesenchymal stem cell-based therapy: Increasing transplanted cell resistance and increasing tissue …

FE Ezquer, ME Ezquer, JM Vicencio… - Cell adhesion & …, 2017 - Taylor & Francis
Over the past 2 decades, therapies based on mesenchymal stem cells (MSC) have been
tested to treat several types of diseases in clinical studies, due to their potential for tissue …

Biological differences between native and cultured mesenchymal stem cells: implications for therapies

E Jones, R Schäfer - Stem Cell Protocols, 2015 - Springer
We describe the current knowledge of the surface marker phenotype of native bone marrow
mesenchymal stem/stromal cells (MSCs) in humans and in mouse models, highlighting …

Improved therapeutics of modified mesenchymal stem cells: an update

DKW Ocansey, B Pei, Y Yan, H Qian, X Zhang… - Journal of translational …, 2020 - Springer
Abstract Background Mesenchymal stromal cells (MSCs) have attracted intense interest due
to their powerful intrinsic properties of self-regeneration, immunomodulation and multi …

[HTML][HTML] Enhancing survival, engraftment, and osteogenic potential of mesenchymal stem cells

D Garcia-Sanchez, D Fernandez… - World journal of stem …, 2019 - ncbi.nlm.nih.gov
Mesenchymal stem cells (MSCs) are promising candidates for bone regeneration therapies
due to their plasticity and easiness of sourcing. MSC-based treatments are generally …

Experimental strategies of mesenchymal stem cell propagation: adverse events and potential risk of functional changes

K Drela, L Stanaszek, A Nowakowski… - Stem cells …, 2019 - Wiley Online Library
Mesenchymal stem cells (MSCs) are attractive candidates for cell‐based tissue repair
approaches. Hundreds of clinical trials using MSCs have been completed and many others …

The pros and cons of mesenchymal stem cell-based therapies

A Musiał-Wysocka, M Kot, M Majka - Cell transplantation, 2019 - journals.sagepub.com
The need to search for new, alternative treatments for various diseases has prompted
scientists and physicians to focus their attention on regenerative medicine and broadly …

Application of mesenchymal stem cells in regenerative medicine: A new approach in modern medical science

F Ebrahimi, F Pirouzmand… - Biotechnology …, 2023 - Wiley Online Library
Abstract Mesenchymal Stem Cells (MSCs) are non‐hematopoietic and multipotent stem
cells, which have been considered in regenerative medicine. These cells are easily …

[HTML][HTML] Safety and therapeutic potential of human bone marrow-derived mesenchymal stromal cells in regenerative medicine

AP Aithal, LK Bairy, RN Seetharam - Stem cell investigation, 2021 - ncbi.nlm.nih.gov
Regenerative medicine is considered as an alternative approach to healthcare. Owing to
their pluripotent abilities and their relative lack of ethical and legal issues, adult stem cells …

Potential pre-activation strategies for improving therapeutic efficacy of mesenchymal stem cells: current status and future prospects

M Li, Y Jiang, Q Hou, Y Zhao, L Zhong, X Fu - Stem cell research & …, 2022 - Springer
Mesenchymal stem cell (MSC)-based therapy has been considered as a promising
approach targeting a variety of intractable diseases due to remarkable multiple effect of …

Challenges and controversies in human mesenchymal stem cell therapy

B Lukomska, L Stanaszek, E Zuba-Surma… - Stem cells …, 2019 - Wiley Online Library
Stem cell therapy is being intensely investigated within the last years. Expectations are high
regarding mesenchymal stem cell (MSC) treatment in translational medicine. However …