Excessive inflammatory responses can emerge as a potential danger for organisms' health.
Physiological balance between pro-and anti-inflammatory processes constitutes an …

Background Activation of cannabinoid (CB) 1 receptors results in attenuation of
experimental colitis. Our aim was to examine the role of CB2 receptors in experimental …

Direct stimulation of cannabinoid CB1 receptors exerts a protective function in animal
models of inflammatory bowel diseases (IBDs). However, it is not known whether …

This study was performed to assess whether mice lacking the cannabinoid receptor CB1,
CB2 or both receptors show increased susceptibility to TNBS colitis in comparison to …

Activation of cannabinoid receptors (CBs) by endocannabinoids impacts on a number of
gastrointestinal functions. Recent data indicate that CB1 agonists improve 2, 4 …

Background & Aims: Two G-protein—coupled cannabinoid receptors, termed CB1 and CB2,
have been identified and several mammalian enteric nervous systems express CB1 …

Background Cannabinoids are known to reduce intestinal inflammation. Atypical
cannabinoids produce pharmacological effects via unidentified targets. We were interested …

Cannabinoid receptors of type 1 and 2 (CB1 and CB2), endogenous ligands that activate
them (endocannabinoids), and mechanisms for endocannabinoid biosynthesis and …

Oil of mustard (OM) is a potent neuronal activator that is known to elicit visceral hyperalgesia
when given intracolonically, but the full extent to which OM is also proinflammatory in the …

Background Recent studies suggest potential roles of the endocannabinoid system in
gastrointestinal inflammation. Although cannabinoid CB2 receptor expression is increased …