[HTML][HTML] A large-scale causal analysis of gut microbiota and delirium: A Mendelian randomization study

H Yu, X Wan, M Yang, J Xie, K Xu, J Wang… - Journal of Affective …, 2023 - Elsevier
Background Several studies have linked gut microbiota to human brain activity. This study
used Mendelian randomization (MR) to investigate the causal relationship between gut …

Gut microbiota and major depressive disorder: a bidirectional Mendelian randomization

M Chen, CR Xie, YZ Shi, TC Tang, H Zheng - Journal of affective disorders, 2022 - Elsevier
Background Observational studies showed an association between gut microbiota and
depression, but the causality relationship between them is unclear. We aimed to determine …

The association between gut microbiota and postoperative delirium in patients

Y Zhang, K Baldyga, Y Dong, W Song… - Translational …, 2023 - nature.com
Postoperative delirium is a common postoperative complication in older patients, and its
pathogenesis and biomarkers remain largely undetermined. The gut microbiota has been …

Gut microbes and depression: still waiting for godot

TG Dinan, JF Cryan - Brain, Behavior, and Immunity, 2019 - Elsevier
The brain-gut-microbiota axis is viewed by some as a major paradigm shift in mental illness
with the potential for the development of entirely novel therapies, while others have …

[HTML][HTML] Gut microbiota and psychiatric disorders: a two-sample Mendelian randomization study

JJ Ni, Q Xu, SS Yan, BX Han, H Zhang, XT Wei… - Frontiers in …, 2022 - frontiersin.org
Evidence supports the observational associations of gut microbiota with a variety of
psychiatric disorders, but the causal nature of such associations remains obscure. Aiming to …

Gut microbiome-wide association study of depressive symptoms

D Radjabzadeh, JA Bosch, AG Uitterlinden… - Nature …, 2022 - nature.com
Depression is one of the most poorly understood diseases due to its elusive pathogenesis.
There is an urgency to identify molecular and biological mechanisms underlying depression …

Abnormal composition of gut microbiota contributes to delirium‐like behaviors after abdominal surgery in mice

J Zhang, JJ Bi, GJ Guo, L Yang, B Zhu… - CNS Neuroscience …, 2019 - Wiley Online Library
Aims Anesthesia and surgery can cause delirium‐like symptoms postoperatively. Increasing
evidence suggests that gut microbiota is a physiological regulator of the brain. Herein, we …

The gut microbiota and depressive symptoms across ethnic groups

JA Bosch, M Nieuwdorp, AH Zwinderman… - Nature …, 2022 - nature.com
The gut microbiome is thought to play a role in depressive disorders, which makes it an
attractive target for interventions. Both the microbiome and depressive symptom levels vary …

[HTML][HTML] Assessing the effect of interaction between gut microbiome and inflammatory bowel disease on the risks of depression

X Qin, C Pan, Q Cai, Y Zhao, D He, W Wei… - Brain, Behavior, & …, 2022 - Elsevier
Background Gut microbiome and inflammatory bowel disease (IBD) are implicated in the
development of depression, but the effect of their interactions on the risk of depression …

[HTML][HTML] Anesthesia and surgery induce age-dependent changes in behaviors and microbiota

N Liufu, L Liu, S Shen, Z Jiang, Y Dong, Y Wang… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
The neuropathogenesis of postoperative delirium remains mostly unknown. The gut
microbiota is implicated in the pathogenesis of neurological disorders. We, therefore, set out …