A compendium and comparative epigenomics analysis of cis-regulatory elements in the pig genome
Although major advances in genomics have initiated an exciting new era of research, a lack
of information regarding cis-regulatory elements has limited the genetic improvement or …
of information regarding cis-regulatory elements has limited the genetic improvement or …
Pig genome functional annotation enhances the biological interpretation of complex traits and human disease
The functional annotation of livestock genomes is crucial for understanding the molecular
mechanisms that underpin complex traits of economic importance, adaptive evolution and …
mechanisms that underpin complex traits of economic importance, adaptive evolution and …
A compendium of genetic regulatory effects across pig tissues
Abstract The Farm Animal Genotype-Tissue Expression (FarmGTEx) project has been
established to develop a public resource of genetic regulatory variants in livestock, which is …
established to develop a public resource of genetic regulatory variants in livestock, which is …
PigBiobank: a valuable resource for understanding genetic and biological mechanisms of diverse complex traits in pigs
H Zeng, W Zhang, Q Lin, Y Gao, J Teng… - Nucleic acids …, 2024 - academic.oup.com
To fully unlock the potential of pigs as both agricultural species for animal-based protein
food and biomedical models for human biology and disease, a comprehensive …
food and biomedical models for human biology and disease, a comprehensive …
A pig BodyMap transcriptome reveals diverse tissue physiologies and evolutionary dynamics of transcription
A comprehensive transcriptomic survey of pigs can provide a mechanistic understanding of
tissue specialization processes underlying economically valuable traits and accelerate their …
tissue specialization processes underlying economically valuable traits and accelerate their …
Functional annotations of three domestic animal genomes provide vital resources for comparative and agricultural research
Gene regulatory elements are central drivers of phenotypic variation and thus of critical
importance towards understanding the genetics of complex traits. The Functional Annotation …
importance towards understanding the genetics of complex traits. The Functional Annotation …
Mapping and analysis of a spatiotemporal H3K27ac and gene expression spectrum in pigs
Y Zhu, Z Zhou, T Huang, Z Zhang, W Li, Z Ling… - Science China Life …, 2022 - Springer
The limited knowledge of genomic noncoding and regulatory regions has restricted our
ability to decipher the genetic mechanisms underlying complex traits in pigs. In this study …
ability to decipher the genetic mechanisms underlying complex traits in pigs. In this study …
Enhancer-promoter interaction maps provide insights into skeletal muscle-related traits in pig genome
J Li, Y Xiang, L Zhang, X Qi, Z Zheng, P Zhou, Z Tang… - BMC biology, 2022 - Springer
Background Gene expression programs are intimately linked to the interplay of active cis
regulatory elements mediated by chromatin contacts and associated RNAs. Genome-wide …
regulatory elements mediated by chromatin contacts and associated RNAs. Genome-wide …
An atlas of regulatory elements in chicken: A resource for chicken genetics and genomics
A comprehensive characterization of regulatory elements in the chicken genome across
tissues will have substantial impacts on both fundamental and applied research. Here, we …
tissues will have substantial impacts on both fundamental and applied research. Here, we …
A gene expression atlas of the domestic pig
TC Freeman, A Ivens, JK Baillie, D Beraldi, MW Barnett… - BMC biology, 2012 - Springer
Background This work describes the first genome-wide analysis of the transcriptional
landscape of the pig. A new porcine Affymetrix expression array was designed in order to …
landscape of the pig. A new porcine Affymetrix expression array was designed in order to …