Cytokines play an important part in many pathobiological processes of chronic obstructive
pulmonary disease (COPD), including the chronic inflammatory process, emphysema, and …

Although long-acting bronchodilators have been an important advance for the management
of chronic obstructive pulmonary disease (COPD), these drugs do not deal with the …

Chronic obstructive pulmonary disease (COPD) is an inflammatory lung disease associated
with progressive airflow limitation. The main risk factor is tobacco smoking. Anti-inflammatory …

COPD is a major health problem, with patients showing a progressively declining, largely
irreversible, change in lung function. This is associated with chronic airways inflammation …

Chronic obstructive pulmonary disease [COPD] is characterised by airflow limitation of
peripheral airways that is not fully reversible and progressive and is associated with an …

The management of chronic obstructive pulmonary disease (COPD) is fundamentally still
heavily dependent on the use of bronchodilators and corticosteroids. Therefore, there is a …

No currently available treatments reduce the progression or suppress the inflammation of
chronic obstructive pulmonary disease (COPD). However, with a better understanding of the …

Chronic obstructive pulmonary disease (COPD) is a major global health problem which is
increasing throughout the world and a major cause of death. However, current therapies fail …

The mainstay of current drug therapy is long-acting bronchodilators; several longer acting
inhaled β 2-agonists and muscarinic antagonists (and combinations) are now in …

Study objective: To investigate the efficacy and safety of a fully human monoclonal antibody
recognizing the chemokine interleukin (IL)-8 in patients with COPD. Design: Randomized …