Shigella spp. are one of the leading causes of infectious diarrheal diseases. They are
Escherichia coli pathovars that are characterized by the harboring of a large plasmid that …

Shigella comprises four species of human-restricted pathogens causing bacillary dysentery.
While Shigella possesses multiple genetic loci contributing to virulence, a type III secretion …

Type III secretion systems (T3SSs) mediate bacterial protein translocation into eukaryotic
cells, a process essential for virulence of many Gram-negative pathogens. They are …

Type III secretion systems (T3SSs) are key determinants of virulence in many Gram‐
negative bacteria, including animal and plant pathogens. They inject 'effector'proteins …

Bacterial Type III Secretion Systems (T3SSs) are specialized multicomponent
nanomachines that mediate the transport of proteins either to extracellular locations or …

Type III secretion systems (T3SSs) are essential virulence determinants of many Gram‐
negative bacterial pathogens. The Shigella T3SS consists of a cytoplasmic bulb, a …

Abstract The Shigella flexneri Type III secretion system (T3SS) senses contact with human
intestinal cells and injects effector proteins that promote pathogen entry as the first step in …

Shigella spp. are Gram-negative bacterial pathogens that infect human colonic epithelia and
cause bacterial dysentery. These bacteria express multiple copies of a syringe-like protein …

The Type III Secretion System (T3SS) is a macromolecular complex used by Gram-negative
bacteria to secrete effector proteins from the cytoplasm across the bacterial envelope in a …

Numerous Gram-negative bacterial pathogens utilize type III secretion systems (T3SSs) to
inject tens of effector proteins directly into the cytosol of host cells. Through interactions with …