Adult T-cell leukemia-lymphoma (ATL), is a highly malignant T-cell neoplasm caused by
human T-cell leukemia virus type 1 (HTLV-1), characterized by poor prognosis. Two viral …

Human T cell lymphotropic virus type 1 (HTLV-1) is the causative agent of adult T cell
leukemia/lymphoma (ATL) and HTLV-1-associated myelopathy/tropical spastic paraparesis …

Human T cell leukemia virus type 1 (HTLV-1) is an oncogenic human retrovirus that has
infected 10–15 million people worldwide. After a long latency, 3–5% of infected individuals …

Adult T-cell leukemia (ATL) is an often fatal leukemia of CD4+ T lymphocytes associated
with a complex retrovirus, human T-cell leukemia virus type 1 (HTLV-1). Although the viral …

Adult T-cell leukemia/lymphoma (ATLL) is caused by human T-cell leukemia virus type 1
(HTLV-1). HTLV-1-associated mRNA, including HBZ and tax, is deeply involved in the …

Background Recently, human T-cell leukemia virus type 1 (HTLV-1) basic leucine zipper
factor (HBZ), encoded from a minus strand mRNA was discovered and was suggested to …

Adult T‐cell leukemia/lymphoma (ATLL) is a T‐cell malignancy associated with HTLV‐1. The
HTLV‐1 provirus genome has the pX region that encodes tax and HTLV‐1 basic leucine …

Highlights•HTLV-1 primarily transmits by cell-to-cell contact.•HTLV-1 increases the number
of infected cells by clonal proliferation to facilitate its transmission.•HTLV-1 bZIP factor (HBZ) …

Adult T-cell leukemia (ATL) was first described in 1977. A link between ATL and human T-
cell leukemia virus type 1 (HTLV-1) was clearly established in the early 1980s. Over the …

The human T-cell leukemia virus type 1 (HTLV-1) is the only known human oncogenic
retrovirus. HTLV-1 can cause a type of cancer called adult T-cell leukemia/lymphoma (ATL) …