Research and diagnostics for medically relevant tandem repeats and repeat expansions are
hampered by the lack of population-scale databases. We attempt to fill this gap using our …

Short tandem repeats (STRs) are widely present in the human genome. Studies have
confirmed that STRs are associated with more than 30 diseases, and they have also been …

More than 50 neurological and neuromuscular diseases are caused by short tandem repeat
(STR) expansions, with 37 different genes implicated to date. We describe the use of …

Background Long-read nanopore sequencing technology is of particular significance for
taxonomic identification at or below the species level. For many environmental samples, the …

Tandem repeats are frequent across the human genome, and variation in repeat length has
been linked to a variety of traits. Recent improvements in long read sequencing …

Tandem repeats are frequent across the human genome, and variation in repeat length has
been linked to a variety of traits. Recent improvements in long read sequencing …

Tandem repeat sequences comprise approximately 8% of the human genome and are
linked to more than 50 neurodegenerative disorders. Accurate characterization of disease …

Forensic short-tandem repeats (STR) genetic markers are multi-allelic, and widely utilized
for in individual identification, kinship testing, and cell-line authentication. Nanopore …

Nucleic acid sequencing is the process of identifying the sequence of DNA or RNA, with
DNA used for genomes and RNA for transcriptomes. Deciphering this information has the …

Background Tandem repeats are highly mutable and contribute to the development of
human disease by a variety of mechanisms. It is difficult to predict which tandem repeats …