Ruthenium‐and silver‐catalyzed selective C–H alkenylations, thiolations and selenylations
of phenazone (antipyrine)–a non‐steroidal anti‐inflammatory drug–have been developed …

Ruthenium (II)-catalyzed C (sp2)–H functionalization of N-aryl phthalazinones with a range
of aldehydes and activated ketone is described. Initial formation of hydroxyalkylated …

A general method is reported for the stereoselective preparation of highly functionalized
allylic thioethers. This protocol is based on a Pd-catalyzed thiolation of modular vinyl cyclic …

The catalyst-free sp3 C–H functionalization of 2-alkylazaarenes has been achieved in the
reaction with (thio) coumarin-3-carboxylic acids. Followed by a tandem decarboxylation, this …

We report a transition metal-free approach for the regioselective functionalization of benzylic
C (sp3)–H bonds using alcohols and carboxylic acids as the nucleophiles. This …

The efficient palladium-catalyzed synthesis of esters from readily available arenes has been
developed. These C–H bond esterifications were achieved relying on the regioselective …

A Pd-catalyzed alkenyl thioether synthesis was achieved using thioesters and N-
tosylhydrazones as starting materials. The thioester acted as an efficient “sulfur source” for …

Site-selective intermolecular C–H bond functionalization is of central importance to synthetic
chemistry. In particular, direct β-functionalization of N-heterocycles still remains a great …

The first example of transition-metal-catalyzed C–H activations of 2-phenylisatogens with
alkynes and sulfonyl azides has been developed using N-oxide as the directing group. Ru …

A new methodology was developed to access isothiazolone derivatives from simple
acrylamides by transition metal catalyzed C–H bond functionalization. This Pd-catalyzed …