A key focus in 21st century integrative biology and drug discovery for neglected tropical and
other diseases has been the use of BLAST-based computational methods for identification …

Abstract eggNOG is a public resource that provides Orthologous Groups (OGs) of proteins at
different taxonomic levels, each with integrated and summarized functional annotations …

Abstract OrthoDB (https://www. orthodb. org) provides evolutionary and functional
annotations of orthologs. This update features a major scaling up of the resource coverage …

Background Homology inference helps on identifying similarities, as well as differences
among organisms, which provides a better insight on how closely related one might be to …

Abstract eggNOG is a public database of orthology relationships, gene evolutionary histories
and functional annotations. Here, we present version 5.0, featuring a major update of the …

OrthoDB provides evolutionary and functional annotations of orthologs, inferred for a vast
number of available organisms. OrthoDB is leading in the coverage and genomic diversity …

Orthology, refining the concept of homology, is the cornerstone of evolutionary comparative
studies. With the ever-increasing availability of genomic data, inference of orthology has …

Abstract The Eukaryotic Pathogen, Vector and Host Informatics Resource (VEuPathDB,
https://veupathdb. org) is a Bioinformatics Resource Center funded by the National Institutes …

OrthoDB provides evolutionary and functional annotations of genes in a diverse sampling of
eukaryotes, prokaryotes, and viruses. Genomics continues to accelerate our exploration of …

Background The initial step to interpreting putative biological functions from comparative
multi-omics studies usually starts from a differential expressed gene list followed by …