Serotonin syndrome: pathophysiology, clinical features, management, and potential future directions

WJ Scotton, LJ Hill, AC Williams… - International Journal of …, 2019 - journals.sagepub.com
Serotonin syndrome (SS)(also referred to as serotonin toxicity) is a potentially life-
threatening drug-induced toxidrome associated with increased serotonergic activity in both …

Drug-induced serotonin syndrome: a review

C Sun-Edelstein, SJ Tepper… - Expert opinion on drug …, 2008 - Taylor & Francis
Serotonin syndrome, or serotonin toxicity (ST), is a clinical condition that occurs as a result of
an iatrogenic drug-induced increase in intrasynaptic serotonin levels primarily resulting in …

Serotonin syndrome

J Volpi-Abadie, AM Kaye, AD Kaye - Ochsner Journal, 2013 - ochsnerjournal.org
Background Serotonin syndrome is a potentially life-threatening syndrome that is
precipitated by the use of serotonergic drugs and overactivation of both the peripheral and …

Overview of serotonin syndrome

MM Iqbal, MJ Basil, J Kaplan, MD Iqbal - , 24, 4, 2012 - ingentaconnect.com
BACKGROUND: Serotonin syndrome (SS) is a rare and potentially life-threatening toxic
state caused by an adverse drug reaction that leads to excessive central and peripheral …

The serotonin syndrome: implicated drugs, pathophysiology and management

KA Sporer - Drug safety, 1995 - Springer
The serotonin syndrome has increasingly been recognised in patients who have received
combined serotonergic drugs. This syndrome is characterised by a constellation of …

Serotonin syndrome: a complex but easily avoidable condition

Y Dvir, P Smallwood - General hospital psychiatry, 2008 - Elsevier
Serotonin syndrome is a potentially life-threatening adverse drug reaction caused by
excessive serotonergic agonism in central and peripheral nervous system serotonergic …

Demystifying serotonin syndrome (or serotonin toxicity)

AL Foong, KA Grindrod, T Patel, J Kellar - Canadian Family Physician, 2018 - cfp.ca
Objective To review the symptoms of serotonin toxicity (commonly referred to as serotonin
syndrome) and the causative drugs and their mechanisms of action, and to equip primary …

The serotonin toxidrome: shortfalls of current diagnostic criteria for related syndromes

AL Chiew, NA Buckley - Clinical Toxicology, 2022 - Taylor & Francis
Introduction Serotonin syndrome (toxicity) describes adverse drug effects from toxic amounts
of intra-synaptic central nervous system serotonin. A wide range of drugs have been …

The pathophysiology of serotonin toxicity in animals and humans: implications for diagnosis and treatment

GK Isbister, NA Buckley - Clinical neuropharmacology, 2005 - journals.lww.com
Serotonin toxicity (or serotonin syndrome) has become an increasingly common and
important clinical problem in medicine over the last 15 years with the introduction of many …

The serotonin syndrome

EW Boyer, M Shannon - New England Journal of Medicine, 2005 - Mass Medical Soc
The Serotonin Syndrome | New England Journal of Medicine Skip to main content Access
provided byUT MD ANDERSON CANCER CENTER The New England Journal of Medicine …