Background Ferroptosis in alveolar and bronchial epithelial cells is one of the main
mechanisms underlying the development of chronic obstructive pulmonary disease (COPD) …

Cigarette smoke (CS)-caused ferroptosis was involved in the pathogenesis of COPD, but the
role of ferroptosis in lung epithelial injury and inflammation is not clear. Rats were treated …

Background It is now understood that ferroptosis plays a significant role in the progression of
chronic obstructive pulmonary disease (COPD) induced by cigarette smoke extract (CSE) …

Background Dihydroquercetin (DHQ) is a flavonoid with strong anti-inflammatory and
antioxidant effects. However, its protective activity against cigarette smoke-induced …

Cigarette smoke is responsible for many fatal pulmonary diseases, however, the toxic
mechanism is still unclear. In this study, we first confirmed that whole cigarette smoke …

Ferroptosis is a kind of regulated cell death, supporting the pathological process of lung
inflammation, including asthma. Quercetin (QCT), a kind of natural dietary flavonoid, exerts …

Background: Cigarette smoking is a major risk factor for bronchoalveolar epithelial cell
(BAEC) injury. Understanding the relevant pathogenesis is important for the treatment of …

Acute lung injury (ALI) causes high morbidity and mortality rates in critically ill patients, and
there are currently no effective therapeutic drugs. Ferroptosis is a newly discovered mode of …

Background PM 2.5 is a well-known harmful air pollutant that can lead to acute exacerbation
and aggravation of respiratory diseases. Although ferroptosis is involves in the pathological …

Activating angiotensin-converting enzyme 2 (ACE2) is an important player in the
pathogenesis of septic-related acute respiratory distress syndrome (ARDS). Rosmarinic acid …