[HTML][HTML] Effect of size and surface charge of gold nanoparticles on their skin permeability: a molecular dynamics study

R Gupta, B Rai - Scientific reports, 2017 - nature.com
Molecular level understanding of permeation of nanoparticles through human skin
establishes the basis for development of novel transdermal drug delivery systems and …

Penetration of gold nanoparticles through human skin: unraveling its mechanisms at the molecular scale

R Gupta, B Rai - The Journal of Physical Chemistry B, 2016 - ACS Publications
Recent experimental studies suggest that nanosized gold nanoparticles (AuNPs) are able to
penetrate into the deeper layer (epidermis and dermis) of rat and human skin. However, the …

Gold nanoparticles for skin drug delivery

Y Chen, X Feng - International Journal of Pharmaceutics, 2022 - Elsevier
Nanoparticle-based drug carriers are being pursued intensely to overcome the skin barrier
and improve even hydrophilic or macromolecular drug delivery into or across the skin …

Interactions of skin with gold nanoparticles of different surface charge, shape, and functionality

R Fernandes, NR Smyth, OL Muskens, S Nitti… - Small, 2015 - Wiley Online Library
The interactions between skin and colloidal gold nanoparticles of different physicochemical
characteristics are investigated. By systematically varying the charge, shape, and …

[HTML][HTML] Physical properties of gold nanoparticles affect skin penetration via hair follicles

N Friedman, A Dagan, J Elia, S Merims… - … , Biology and Medicine, 2021 - Elsevier
Drug penetration through the skin is significant for both transdermal and dermal delivery.
One mechanism that has attracted attention over the last two decades is the transport …

Influence of surface charge of gold nanorods on skin penetration

O Lee, SH Jeong, WU Shin, G Lee… - Skin research and …, 2013 - Wiley Online Library
Background/purpose The skin plays an important role as a protective barrier against toxic
environments and also is a route of drug administration. In spite of evidence for and interest …

In Silico Study of Gold Nanoparticle Uptake into a Mammalian Cell: Interplay of Size, Shape, Surface Charge, and Aggregation

T Lunnoo, J Assawakhajornsak… - The Journal of Physical …, 2019 - ACS Publications
The study of interactions between Au nanostructures and living cells is a fundamental aspect
that can be applied for promising applications in nanomedicine. In the present work, we …

Co-administration of protein drugs with gold nanoparticles to enable percutaneous delivery

Y Huang, F Yu, YS Park, J Wang, MC Shin, HS Chung… - Biomaterials, 2010 - Elsevier
An interesting nanoscale interfacial phenomenon mediated by gold nanoparticles (Au-NPs)
was found, in that co-administration with Au-NPs enables percutaneous delivery of protein …

Mechanism and determinants of nanoparticle penetration through human skin

HI Labouta, LK El-Khordagui, T Kraus, M Schneider - Nanoscale, 2011 - pubs.rsc.org
The ability of nanoparticles to penetrate the stratum corneum was the focus of several
studies. Yet, there are controversial issues available for particle penetration due to different …

Nanoparticle translocation through a lipid bilayer tuned by surface chemistry

EL da Rocha, GF Caramori, CR Rambo - Physical chemistry chemical …, 2013 - pubs.rsc.org
An enhanced understanding about the interactions between nanomaterials and cell
membranes may have important implications for biomedical applications. In this work …