Chronic myelogenous leukemia: biology and therapy

S Faderl, M Talpaz, Z Estrov… - Annals of internal …, 1999 - acpjournals.org
Chronic myelogenous leukemia is a myeloproliferative disorder. It is characterized by a
biphasic or triphasic clinical course in which a benign chronic phase is followed by …

Chronic myelogenous leukemia: update on biology and treatment.

S Faderl, HM Kantarjian, M Talpaz - Oncology (Williston Park, NY), 1999 - europepmc.org
Chronic myelogenous leukemia (CML) is a myeloproliferative disorder that follows a
characteristic clinical course in which a chronic phase of variable duration precedes an …

Clonal evolution in chronic myelogenous leukemia

J Cortes, ME O'Dwyer - Hematology/Oncology Clinics, 2004 - hemonc.theclinics.com
Chronic myelogenous leukemia (CML) is a clonal hematopoietic stem cell disorder
characterized by a specific chromosomal translocation, t (9; 22), that results in a shortened …

Molecular pathogenesis of chronic myeloid leukemia: implications for new therapeutic strategies

M Warmuth, S Danhauser-Riedl, M Hallek - Annals of Hematology, 1999 - Springer
With an annual incidence of about ten in 1,000,000 people, chronic myeloid leukemia (CML)
accounts for most cases of myeloproliferative disease and for 20% of all leukemias. While …

The biology of chronic myeloid leukemia

S Faderl, M Talpaz, Z Estrov, S O'Brien… - … England Journal of …, 1999 - Mass Medical Soc
Chronic myeloid leukemia (CML) is a clonal myeloproliferative expansion of transformed,
primitive hematopoietic progenitor cells. It involves myeloid, monocytic, erythroid …

[HTML][HTML] Chronic myeloid leukaemia in the 21st century

R Frazer, AE Irvine, MF McMullin - The Ulster medical journal, 2007 - ncbi.nlm.nih.gov
Chronic Myeloid Leukaemia (CML) is a clonal, myeloproliferative disease that develops
when a single, pluripotential, haemopoetic stem cell acquires the Philadelphia chromosome …

Chronic myelogenous leukemia

M Kalidas, H Kantarjian, M Talpaz - Jama, 2001 - jamanetwork.com
Chronic myelogenous leukemia classically progresses through 3 phases, becoming more
resistant to treatment in each successive phase. The majority of patients present in the …

[HTML][HTML] Chronic myeloid leukemia: reminiscences and dreams

TI Mughal, JP Radich, MW Deininger, JF Apperley… - …, 2016 - ncbi.nlm.nih.gov
With the deaths of Janet Rowley and John Goldman in December 2013, the world lost two
pioneers in the field of chronic myeloid leukemia. In 1973, Janet Rowley, unraveled the …

Clinical and epidemiologic burden of chronic myelogenous leukemia

A Redaelli, C Bell, J Casagrande… - Expert review of …, 2004 - Taylor & Francis
Chronic myelogenous leukemia represents 7–20% of all leukemia cases, with a worldwide
incidence projected at less than one to two per 100,000 people. Approximately 85% of …

Chronic myelogenous leukaemia.

SJ Lee - British journal of haematology, 2000 - europepmc.org
In the last decade, improvements in both non-transplant and transplant therapy have
extended the lives of patients with CML, particularly those in chronic phase. The future will …