Integrated point-of-care molecular diagnostic devices for infectious diseases

W Liu, F Yue, LP Lee - Accounts of chemical research, 2021 - ACS Publications
Conspectus The global outbreaks of deadly infectious diseases caused by pathogenic
microorganisms have threatened public health worldwide and significantly motivated …

Advances in Simple, Rapid, and Contamination-Free Instantaneous Nucleic Acid Devices for Pathogen Detection

Y Wang, C Wang, Z Zhou, J Si, S Li, Y Zeng, Y Deng… - Biosensors, 2023 - mdpi.com
Pathogenic pathogens invade the human body through various pathways, causing damage
to host cells, tissues, and their functions, ultimately leading to the development of diseases …

A robust, hand-powered, instrument-free sample preparation system for point-of-care pathogen detection

F Zhao, EY Lee, GS Noh, J Shin, H Liu, Z Qiao… - Scientific reports, 2019 - nature.com
Here, we describe a simple, universal protocol for use in nucleic acid testing-based
pathogen diagnostics, which requires only hand-powered sample preparation, including the …

[HTML][HTML] Pathogen detection on microfluidic platforms: Recent advances, challenges, and prospects

A Jagannath, H Cong, J Hassan, G Gonzalez… - … and Bioelectronics: X, 2022 - Elsevier
Abstract Point-Of-Care (POC) testing has advanced to more affordable and rapid
alternatives by adapting conventional immunoassays and molecular assays (isothermal …

Microfluidics-based strategies for molecular diagnostics of infectious diseases

X Wang, XZ Hong, YW Li, Y Li, J Wang, P Chen… - Military Medical …, 2022 - Springer
Traditional diagnostic strategies for infectious disease detection require benchtop
instruments that are inappropriate for point-of-care testing (POCT). Emerging microfluidics, a …

Advances in point-of-care nucleic acid extraction technologies for rapid diagnosis of human and plant diseases

R Paul, E Ostermann, Q Wei - Biosensors and bioelectronics, 2020 - Elsevier
Global health and food security constantly face the challenge of emerging human and plant
diseases caused by bacteria, viruses, fungi, and other pathogens. Disease outbreaks such …

Point of care sensors for infectious pathogens

M Sharafeldin, JJ Davis - Analytical Chemistry, 2020 - ACS Publications
In the wake of the COVID-19 pandemic, the World Health Organization (WHO) has called for
an urgent global collaboration to develop fast, simple, and accurate tests capable of curbing …

Microfluidic platform towards point-of-care diagnostics in infectious diseases

W Su, X Gao, L Jiang, J Qin - Journal of Chromatography A, 2015 - Elsevier
Rapid and timely diagnosis of infectious diseases is a critical determinant of clinical
outcomes and general public health. For the detection of various pathogens, microfluidics …

Advances in microfluidic PCR for point-of-care infectious disease diagnostics

S Park, Y Zhang, S Lin, TH Wang, S Yang - Biotechnology advances, 2011 - Elsevier
Global burdens from existing or emerging infectious diseases emphasize the need for point-
of-care (POC) diagnostics to enhance timely recognition and intervention. Molecular …

Smart cup: a minimally-instrumented, smartphone-based point-of-care molecular diagnostic device

SC Liao, J Peng, MG Mauk, S Awasthi, J Song… - Sensors and Actuators B …, 2016 - Elsevier
Nucleic acid amplification-based diagnostics offer rapid, sensitive, and specific means for
detecting and monitoring the progression of infectious diseases. However, this method …