Small-cell lung cancer: what we know, what we need to know and the path forward
Small-cell lung cancer (SCLC) is a deadly tumour accounting for approximately 15% of lung
cancers and is pathologically, molecularly, biologically and clinically very different from other …
cancers and is pathologically, molecularly, biologically and clinically very different from other …
Advances in small-cell lung cancer (SCLC) translational research
BJ Drapkin, CM Rudin - Cold Spring …, 2021 - perspectivesinmedicine.cshlp.org
Over the past several years, we have witnessed a resurgence of interest in the biology and
therapeutic vulnerabilities of small-cell lung cancer (SCLC). This has been driven in part …
therapeutic vulnerabilities of small-cell lung cancer (SCLC). This has been driven in part …
Small cell lung cancer: where do we go from here?
Small cell lung cancer (SCLC) is an aggressive disease that accounts for approximately
14% of all lung cancers. In the United States, approximately 31,000 patients are diagnosed …
14% of all lung cancers. In the United States, approximately 31,000 patients are diagnosed …
[HTML][HTML] Small cell lung cancer (SCLC): no treatment advances in recent years
F Koinis, A Kotsakis, V Georgoulias - Translational lung cancer …, 2016 - ncbi.nlm.nih.gov
Small cell lung cancer (SCLC) is an aggressive malignancy with a distinct natural history
and dismal prognosis. Given its predisposition for early dissemination, patients are …
and dismal prognosis. Given its predisposition for early dissemination, patients are …
Clinical insights into small cell lung cancer: Tumor heterogeneity, diagnosis, therapy, and future directions
Z Megyesfalvi, CM Gay, H Popper… - CA: a cancer journal …, 2023 - Wiley Online Library
Small cell lung cancer (SCLC) is characterized by rapid growth and high metastatic capacity.
It has strong epidemiologic and biologic links to tobacco carcinogens. Although the majority …
It has strong epidemiologic and biologic links to tobacco carcinogens. Although the majority …
Small cell lung cancer: will recent progress lead to improved outcomes?
Small cell lung cancer (SCLC) is an aggressive neuroendocrine malignancy with a unique
natural history characterized by a short doubling time, high growth fraction, and early …
natural history characterized by a short doubling time, high growth fraction, and early …
[HTML][HTML] Small cell lung cancer: can recent advances in biology and molecular biology be translated into improved outcomes?
Small cell lung cancer (SCLC) is one of the four major histological types of lung cancer. The
incidence of SCLC in developed countries has declined in recent years, presumably …
incidence of SCLC in developed countries has declined in recent years, presumably …
Small-cell lung cancer
CM Rudin, E Brambilla, C Faivre-Finn… - Nature Reviews Disease …, 2021 - nature.com
Small-cell lung cancer (SCLC) represents about 15% of all lung cancers and is marked by
an exceptionally high proliferative rate, strong predilection for early metastasis and poor …
an exceptionally high proliferative rate, strong predilection for early metastasis and poor …
Advances in small cell lung cancer
GP Kalemkerian, BJ Schneider - Hematology/Oncology …, 2017 - hemonc.theclinics.com
Small cell lung cancer (SCLC) is an aggressive neuroendocrine tumor with clinical and
pathologic characteristics distinct from those of non-SCLC. The primary cause of SCLC is …
pathologic characteristics distinct from those of non-SCLC. The primary cause of SCLC is …
[HTML][HTML] Small cell lung cancer: novel treatments beyond immunotherapy
JJ Meijer, A Leonetti, G Airò, M Tiseo, C Rolfo… - Seminars in cancer …, 2022 - Elsevier
Small cell lung cancer (SCLC) arises in peribronchial locations and infiltrates the bronchial
submucosa, including about 15% of lung cancer cases. Despite decades of research, the …
submucosa, including about 15% of lung cancer cases. Despite decades of research, the …