Abstract The Na+/I− symporter (NIS) is the plasma membrane glycoprotein that mediates
active I− transport in the thyroid and other tissues, such as salivary glands, stomach …

Abstract The Na+/I− symporter (NIS) is an integral plasma membrane glycoprotein that
mediates active I− transport into the thyroid follicular cells, the first step in thyroid hormone …

Active iodide (I−) transport in both the thyroid and some extrathyroidal tissues is mediated by
the Na+/I− symporter (NIS). In the thyroid, NIS-mediated I− uptake plays a pivotal role in …

The Na+/I− symporter (NIS) is a plasma membrane glycoprotein that mediates active iodide
uptake in the thyroid—the essential first step in thyroid hormone biosynthesis—and in other …

Abstract The Na+/I− symporter (NIS) is an intrinsic plasma membrane protein that mediates
the active transport of I− in the thyroid, lactating mammary gland, stomach and salivary …

Abstract The Na+/I− symporter (NIS) catalyzes the accumulation of iodide into thyroid cells,
an essential step in the biosynthesis of thyroid hormones. As a result of the isolation of the …

The Na+/I− symporter (NIS) is an intrinsic membrane protein that mediates the active
transport of iodide into the thyroid and other tissues, such as salivary glands, gastric …

Absorption of dietary iodide, presumably in the small intestine, is the first step in iodide (I−)
utilization. From the bloodstream, I− is actively taken up via the Na+/I− symporter (NIS) in the …

The active transport of iodide into the thyroid is mediated by the Na+–I− symporter (NIS), an
intrinsic membrane protein. NIS plays key roles in thyroid pathophysiology as the route by …

Context: Terminal differentiation of the human thyroid is characterized by the onset of follicle
formation and thyroid hormone synthesis at 11 gestational weeks (GW). Objective: This …