Assessing spatial learning and memory in rodents

CV Vorhees, MT Williams - ILAR journal, 2014 - academic.oup.com
Maneuvering safely through the environment is central to survival of almost all species. The
ability to do this depends on learning and remembering locations. This capacity is encoded …

Value of water mazes for assessing spatial and egocentric learning and memory in rodent basic research and regulatory studies

CV Vorhees, MT Williams - Neurotoxicology and teratology, 2014 - Elsevier
Maneuvering safely through the environment is central to survival of all animals. The ability
to do this depends on learning and remembering locations. This capacity is encoded in the …

Variants of the Morris water maze task to comparatively assess human and rodent place navigation

R Schoenfeld, T Schiffelholz, C Beyer, B Leplow… - … of Learning and …, 2017 - Elsevier
Performance in the Morris water maze has been widely used in routine behavioural studies
of rodents. Since the advent of computer-based virtual environments, adaptations of the …

Navigation in a “virtual” maze: Sex differences and correlation with psychometric measures of spatial ability in humans

SD Moffat, E Hampson, M Hatzipantelis - Evolution and Human Behavior, 1998 - Elsevier
This study used computer-generated (“virtual”) mazes to investigate sex differences in the
efficiency of spatial route learning in humans. Correlations between maze performance and …

Navigation and acquisition of spatial knowledge in a virtual maze

S Gillner, HA Mallot - Journal of cognitive neuroscience, 1998 - direct.mit.edu
Spatial behavior in humans and animals includes a wide variety of behavioral competences
and makes use of a large number of sensory cues. Here we studied the ability of human …

Spatial navigation (water maze) tasks

AV Terry Jr - Methods of behavior analysis in neuroscience, 2009 - books.google.com
Since the early part of the 20th century, a variety of experimental procedures have been
developed for animals that employ the escape from water as a means to motivate learning …

Memory for places: A navigational model in support of Marr's theory of hippocampal function

M Recce, KD Harris - Hippocampus, 1996 - Wiley Online Library
In this report we describe a model that applies Marr's theory of hippocampal function to the
problem of map‐based navigation. Like many others we attribute a spatial memory function …

Landmark discrimination learning in the dog

NW Milgram, B Adams, H Callahan, E Head… - Learning & …, 1999 - learnmem.cshlp.org
Allocentric spatial memory was studied in dogs of varying ages and sources using a
landmark discrimination task. The primary goal of this study was to develop a protocol to test …

Formation of a place learning-set by the rat: a new paradigm for neurobehavioral studies

IQ Whishaw - Physiology & Behavior, 1985 - Elsevier
The Morris water swimming task provides an ideal way of studying spatial navigational
abilities in rats. It requires that rats swim to find a platform located just below the surface of …

Assessment of spatial learning abilities of mice in a new circular maze

G Koopmans, A Blokland, P van Nieuwenhuijzen… - Physiology & …, 2003 - Elsevier
In the present study, we tested the spatial learning behavior of four different mouse strains
(129/Sv, BALB/c, C57BL and Swiss) in a newly developed circular maze. The maze was …