Eosinophilic airway diseases: from pathophysiological mechanisms to clinical practice

M Mormile, I Mormile, S Fuschillo, FW Rossi… - International Journal of …, 2023 - mdpi.com
Eosinophils play a key role in airway inflammation in many diseases, such as allergic and
non-allergic asthma, chronic rhinosinusitis with nasal polyps, and chronic obstructive …

Eosinophilic Asthma: pathophysiology and Therapeutic Horizons

M Hussain, G Liu - Cells, 2024 - mdpi.com
Asthma is a prevalent chronic non-communicable disease, affecting approximately 300
million people worldwide. It is characterized by significant airway inflammation …

Eosinophilic airway inflammation: role in asthma and chronic obstructive pulmonary disease

L George, CE Brightling - Therapeutic advances in chronic …, 2016 - journals.sagepub.com
The chronic lung diseases, asthma and chronic obstructive pulmonary disease (COPD), are
common affecting over 500 million people worldwide and causing substantial morbidity and …

Eosinophilic inflammation: An appealing target for pharmacologic treatments in severe asthma

A Vatrella, A Maglio, C Pelaia, L Ciampo, G Pelaia… - Biomedicines, 2022 - mdpi.com
Severe asthma is characterized by different endotypes driven by complex pathologic
mechanisms. In most patients with both allergic and non-allergic asthma, predominant …

Severe eosinophilic asthma

A Bakakos, S Loukides, P Bakakos - Journal of clinical medicine, 2019 - mdpi.com
Asthma is a heterogeneous disease with varying severity. Severe asthma is a subject of
constant research because it greatly affects patients' quality of life, and patients with severe …

Eosinophilic asthma, phenotypes-endotypes and current biomarkers of choice

K Porpodis, I Tsiouprou, A Apostolopoulos… - Journal of Personalized …, 2022 - mdpi.com
Asthma phenotyping and endotyping are constantly evolving. Currently, several biologic
agents have been developed towards a personalized approach to asthma management …

Eosinophil: a central player in modulating pathological complexity in asthma

P Pritam, S Manna, A Sahu, SS Swain… - Allergologia et …, 2021 - all-imm.com
Eosinophils are the major inflammatory cells which play a crucial role in the development of
allergic and non-allergic asthma phenotypes. Eosinophilic asthma is the most …

Eosinophilic bioactivities in severe asthma

TF Carr, S Berdnikovs, HU Simon, BS Bochner… - World Allergy …, 2016 - Springer
Asthma is clearly related to airway or blood eosinophilia, and asthmatics with significant
eosinophilia are at higher risk for more severe disease. Eosinophils actively contribute to …

Eosinophilic respiratory disorders and the impact of biologics

JS Bernstein, ME Wechsler - Current Opinion in Pulmonary …, 2023 - journals.lww.com
Eosinophilic respiratory disorders and the impact of biologi... : Current Opinion in Pulmonary
Medicine Eosinophilic respiratory disorders and the impact of biologics : Current Opinion in …

[HTML][HTML] Eosinophils and eosinophilic immune dysfunction in health and disease

DJ Jackson, P Akuthota… - European Respiratory …, 2022 - Eur Respiratory Soc
The functions ascribed to eosinophils have classically been limited to host defence against
certain parasitic infections and potentially deleterious effects in the setting of specific …