Periodontitis is an inflammatory disease characterized by periodontal pocket formation and
alveolar bone resorption. Periodontal bone resorption is induced by osteoclasts and …

Periodontitis is a complex, multifactorial process affected by bacterial plaque-components
and host defense mechanisms. Inflammation of the periodontitium may lead the destruction …

Objective and Background Periodontitis is an inflammatory disorder of the supporting tissue
of teeth, which is composed of gingival soft tissue, cementum covering the tooth root …

Background: Receptor activator of nuclear factor‐kappa B (NF‐κB) ligand (RANKL) and
osteoprotegerin (OPG) are critical for homeostatic control of osteoclast activity, suggesting …

Abstract Background and Objectives The receptor activator of NF‐κB ligand‐osteoprotegerin
(RANKL‐OPG) bi‐molecular system is the “bottle‐neck” regulator of osteoclastogenesis and …

Recent research into periodontal disease pathology focuses on the role of receptor activator
of nuclear factor‐κB ligand (RANKL) and osteoprotegerin (OPG) in periodontal bone …

Objectives: The cytokine receptor activator of nuclear factor κB‐ligand (RANKL) has been
involved in both the physiological and pathological regulation of osteoclast life span and …

Periodontitis is based on a complex inflammatory over-response combined with possible
genetic predisposition factors. The RANKL/RANK/OPG signaling pathway is implicated in …

In this issue Bostanci et al.(2007) demonstrate that receptor activator of NF‐κB ligand
(RANKL) and osteoprotegerin (OPG) were oppositely regulated in gingival crevice fluid …

Periodontitis, one of the most common infectious diseases in humans, is characterized by
inflammation of the periodontal tissue and subsequent destruction of the alveolar bone …