Mammalian triacylglycerol metabolism: synthesis, lipolysis, and signaling
RA Coleman, DG Mashek - Chemical reviews, 2011 - ACS Publications
Triacylglycerol (TAG) is the primary unit of energy storage in eukaryotic cells. TAG comprises
more than 90% of the content of white adipocytes, and TAG synthesis is essential in …
more than 90% of the content of white adipocytes, and TAG synthesis is essential in …
Regulation and function of triacylglycerol lipases in cellular metabolism
MJ Watt, GR Steinberg - Biochemical Journal, 2008 - portlandpress.com
The ability to store energy in the form of energy-dense TAG (triacylglycerol) and to mobilize
these stores rapidly during times of low carbohydrate availability (fasting or famine) or during …
these stores rapidly during times of low carbohydrate availability (fasting or famine) or during …
[HTML][HTML] Triacylglycerol metabolism in adipose tissue
M Ahmadian, RE Duncan, K Jaworski… - Future …, 2007 - ncbi.nlm.nih.gov
Triacylglycerol (TAG) in adipose tissue serves as the major energy storage form in higher
eukaryotes. Obesity, resulting from excess white adipose tissue, has increased dramatically …
eukaryotes. Obesity, resulting from excess white adipose tissue, has increased dramatically …
Physiological and nutritional regulation of enzymes of triacylglycerol synthesis
RA Coleman, TM Lewin, DM Muoio - Annual review of nutrition, 2000 - annualreviews.org
Although triacylglycerol stores play the critical role in an organism's ability to withstand fuel
deprivation and are strongly associated with such disorders as diabetes, obesity, and …
deprivation and are strongly associated with such disorders as diabetes, obesity, and …
Enzymes of triacylglycerol synthesis and their regulation
RA Coleman, DP Lee - Progress in lipid research, 2004 - Elsevier
Since the pathways of glycerolipid biosynthesis were elucidated in the 1950's, considerable
knowledge has been gained about the enzymes that catalyze the lipid biosynthetic reactions …
knowledge has been gained about the enzymes that catalyze the lipid biosynthetic reactions …
[HTML][HTML] Lipolysis–a highly regulated multi-enzyme complex mediates the catabolism of cellular fat stores
A Lass, R Zimmermann, M Oberer, R Zechner - Progress in lipid research, 2011 - Elsevier
Lipolysis is the biochemical pathway responsible for the catabolism of triacylglycerol (TAG)
stored in cellular lipid droplets. The hydrolytic cleavage of TAG generates non-esterified fatty …
stored in cellular lipid droplets. The hydrolytic cleavage of TAG generates non-esterified fatty …
Intestinal triacylglycerol synthesis in fat absorption and systemic energy metabolism
CLE Yen, DW Nelson, MI Yen - Journal of lipid research, 2015 - ASBMB
The intestine plays a prominent role in the biosynthesis of triacylglycerol (triglyceride; TAG).
Digested dietary TAG is repackaged in the intestine to form the hydrophobic core of …
Digested dietary TAG is repackaged in the intestine to form the hydrophobic core of …
Triacylglycerol homeostasis: insights from yeast
SD Kohlwein - Journal of Biological Chemistry, 2010 - ASBMB
The endemic increase in lipid-associated disorders such as obesity and type 2 diabetes
mellitus has placed triacylglycerol metabolism and its associated organelle, lipid droplets, in …
mellitus has placed triacylglycerol metabolism and its associated organelle, lipid droplets, in …
How lipid droplets “TAG” along: Glycerolipid synthetic enzymes and lipid storage
Triacylglycerols (TAG) serve as the predominant form of energy storage in mammalian cells,
and TAG synthesis influences conditions such as obesity, fatty liver, and insulin resistance …
and TAG synthesis influences conditions such as obesity, fatty liver, and insulin resistance …
[HTML][HTML] The Drosophila model to interrogate triacylglycerol biology
C Heier, S Klishch, O Stilbytska, U Semaniuk… - … et Biophysica Acta (BBA …, 2021 - Elsevier
The deposition of storage fat in the form of triacylglycerol (TAG) is an evolutionarily
conserved strategy to cope with fluctuations in energy availability and metabolic stress …
conserved strategy to cope with fluctuations in energy availability and metabolic stress …