TTN mutations predict a poor prognosis in patients with thyroid cancer

X Han, J Chen, J Wang, J Xu, Y Liu - Bioscience Reports, 2022 - portlandpress.com
Objective: We aimed to investigate the relationship between titin (TTN) gene mutations and
thyroid cancer (THCA) and to explore the feasibility of the TTN gene as a potential …

Mutations in the TTN Gene are a Prognostic Factor for Patients with Lung Squamous Cell Carcinomas

S Zou, J Ye, S Hu, Y Wei, J Xu - International Journal of General …, 2022 - Taylor & Francis
Purpose To analyze the relationship between titin (TTN) mutation gene and tumor
mutational burden (TMB) and the with prognosis of lung squamous cell carcinomas (LUSC) …

Aggregate analysis based on TCGA: TTN missense mutation correlates with favorable prognosis in lung squamous cell carcinoma

X Cheng, H Yin, J Fu, C Chen, J An, J Guan… - Journal of cancer …, 2019 - Springer
Purpose Lung cancer prevalence with its high mortality rate is a trending topic globally. Non-
small cell lung cancer (NSCLC) is the most common type of lung cancer. The human gene …

Association between TERT promoter mutations and clinical behaviors in differentiated thyroid carcinoma: a systematic review and meta-analysis

J Yang, Y Gong, S Yan, H Chen, S Qin, R Gong - Endocrine, 2020 - Springer
Background The association between telomerase reverse transcriptase (TERT) promoter
mutations and some clinical behaviors in thyroid cancer remains controversial and requires …

Deciphering Prognostic Value of TTN and Its Correlation With Immune Infiltration in Lung Adenocarcinoma

J Chen, Y Wen, H Su, X Yu, R Hong, C Chen… - Frontiers in …, 2022 - frontiersin.org
Background Lung adenocarcinoma (LUAD) is the most common type of lung cancer,
accounting for around 40%. Despite achievements in the treatment approach, the prognosis …

TERT Promoter Mutations and the 8th Edition TNM Classification in Predicting the Survival of Thyroid Cancer Patients

J Park, S Lee, K Kim, H Park, CS Ki, YL Oh, JH Shin… - Cancers, 2021 - mdpi.com
Simple Summary In a cohort study involving 393 patients with differentiated thyroid cancer,
TERT promoter mutations were found to act as an independent poor prognostic factor based …

Proposal of a New Prognostic Model for Differentiated Thyroid Cancer with TERT Promoter Mutations

J Park, S Lee, J Park, H Park, CS Ki, YL Oh, JH Shin… - Cancers, 2021 - mdpi.com
Simple Summary In a cohort study involving 393 patients with differentiated thyroid cancer,
we incorporated the TERT mutational status into AJCC TNM staging 8th edition (TNM-8) …

Titin Mutation Is Associated With Tumor Mutation Burden and Promotes Antitumor Immunity in Lung Squamous Cell Carcinoma

X Xie, Y Tang, J Sheng, P Shu, X Zhu, X Cai… - Frontiers in Cell and …, 2021 - frontiersin.org
Lung squamous cell carcinoma (LUSC) is a leading cause of mobidity and mortality
worldwide. Recently, there was a shift in the treatment pattern of immune therapy in LUSC …

TET1 is a tumor suppressor that inhibits papillary thyroid carcinoma cell migration and invasion

S Yu, Y Yin, S Hong, S Cao, Y Huang… - International journal …, 2020 - Wiley Online Library
Background. Ten‐eleven translocation (TET) enzymes catalyze the oxidation of 5‐
methylcytosine (5mC) to 5‐hydroxymethylcytosine (5hmC) promoting demethylation in cells …

[PDF][PDF] TERT promoter mutations and long-term survival in patients with thyroid cancer

TH Kim, YE Kim, S Ahn, JY Kim, CS Ki… - Endocr Relat …, 2016 - scholar.archive.org
TERT promoter mutations are emerging prognostic biomarkers in multiple cancers and are
found in highly aggressive thyroid cancer. Our aim is to investigate the prognostic value of …