[HTML][HTML] Adaptive spectroscopic visible-light optical coherence tomography for clinical retinal oximetry

I Rubinoff, RV Kuranov, R Fang, Z Ghassabi… - Communications …, 2023 - nature.com
Background Retinal oxygen saturation (sO2) provides essential information about the eye's
response to pathological changes that can result in vision loss. Visible-light optical …

Automated spectroscopic retinal oximetry with visible-light optical coherence tomography

S Pi, A Camino, W Cepurna, X Wei, M Zhang… - Biomedical optics …, 2018 - opg.optica.org
Accurate, quantitative assessment of retinal blood oxygen saturation (sO2) may provide a
useful early indicator of pathophysiology in several ocular diseases. Here, with visible-light …

Retinal oximetry in humans using visible-light optical coherence tomography

S Chen, X Shu, PL Nesper, W Liu, AA Fawzi… - Biomedical optics …, 2017 - opg.optica.org
We measured hemoglobin oxygen saturation (sO_2) in the retinal circulation in healthy
humans using visible-light optical coherence tomography (vis-OCT). The measurements …

Visible-light optical coherence tomography oximetry based on circumpapillary scan and graph-search segmentation

BT Soetikno, L Beckmann, X Zhang… - Biomedical Optics …, 2018 - opg.optica.org
Visible-light optical coherence tomography (vis-OCT) enables retinal oximetry by measuring
the oxygen saturation of hemoglobin (sO_2) from within individual retinal blood vessels. The …

Visible-light optical coherence tomography for retinal oximetry

J Yi, Q Wei, W Liu, V Backman, HF Zhang - Optics letters, 2013 - opg.optica.org
We applied a visible-light spectroscopic optical coherence tomography (vis-OCT) for in vivo
retinal oximetry. To extract hemoglobin oxygen saturation (sO_2) in individual retinal …

Multiple forward scattering reduces the measured scattering coefficient of whole blood in visible-light optical coherence tomography

R Fang, I Rubinoff, HF Zhang - Biomedical Optics Express, 2022 - opg.optica.org
The optical properties of blood encode oxygen-dependent information. Noninvasive optical
detection of these properties is increasingly desirable to extract biomarkers for tissue health …

Intrinsic spectrally-dependent background in spectroscopic visible-light optical coherence tomography

I Rubinoff, RV Kuranov, HF Zhang - Biomedical Optics Express, 2020 - opg.optica.org
Visible-light optical coherence tomography (vis-OCT) has enabled new spectroscopic
applications, such as retinal oximetry, as a result of increased optical absorption and …

Retinal capillary oximetry with visible light optical coherence tomography

S Pi, TT Hormel, X Wei, W Cepurna… - Proceedings of the …, 2020 - National Acad Sciences
Assessing oxygen saturation (sO2) remains challenging but is nonetheless necessary for
understanding retinal metabolism. We and others previously achieved oximetry on major …

Measuring oxygen saturation in retinal and choroidal circulations in rats using visible light optical coherence tomography angiography

S Chen, J Yi, HF Zhang - Biomedical optics express, 2015 - opg.optica.org
Visible light optical coherence tomography (vis-OCT) has demonstrated its capability of
measuring vascular oxygen saturation (sO_2) in vivo. Enhanced by OCT angiography, the …

Monte Carlo investigation of optical coherence tomography retinal oximetry

S Chen, J Yi, W Liu, V Backman… - IEEE transactions on …, 2015 - ieeexplore.ieee.org
Optical coherence tomography (OCT) oximetry explores the possibility to measure retinal
hemoglobin oxygen saturation level (sO 2). We investigated the accuracy of OCT retinal …